Oral Patho 3 Flashcards
where aphthous stomatitis ocurrs
non keratinized mucosa
aphthous stomatitis
canker sore
most common aphthous stomatitis
minor-small shallow, surrounded by erthema
herpes location
hard gingiva
herpetiform aphthous ulcers
no blistering vs herpes, multiple
blistering
not canker sore
treatment of canker sores
corticosteroids most common
squamous cell carcinoma
deadly,30,000 new cases/year
causes of squamous cell carcinoma
tobacco, alcohol, and HPV
most common squamous cell carcinoma
vermillion border/lower lip
malignant cells
rapid/invasive growth, moves (metastasis)
oncogenes
DNA which controls proliferation/metastisis
tumor supressor genes
regulate growth/metastisis
lip scc
most common, cancer on vermillion border (lower lip)
intraoral SCC
gingival and alveolar carcinomas; painless, keratinized, dentures will not fit, post-lateral tongue
metastatic SCC
Metastasis to LN-firm, non-tender, enlarged-FIXED
Oropharyngeal SCC
Tonsillar Region-HPV related
T1 tumor
<2cm
T2
2-4cm
T3
> 4cm
Histopath
epithelial invasion, necrosis (b/c outgrow blood supply), desmoplasia, angiogenesis (invade blood vessels and cause them to grow to them)
distant metastisis
below the clavicle
Staging of Metastatic SCC
Size of LN (T1-T4)
Regional Lymph Node involvement (single vs. multiple and large vs small)
Distant Metastasis (Absent vs. Present)
Most common stage of Metastatic SCC (T1-T4)
T2 and T3
Histopathological Grading
grade tumors at a histopatho level
Grade I
well-differentiated (low grade); tumor resembles normal (origin) tissue
Grade IV
Does not resemble tissue it came from (poorly differentiated and high grade or anaplastic)-HARD to make a diagnosis
Average Five year survival
64%
Who gets Lichen planus
middle aged adults; F>M 2:3
Oral lesions of Lichen Planus
white lace like dots on the insides of the cheeks and tongue, peeling
Reticular Oral LP
Striations, papules, plaques
Erosive Oral LP
Less common, symptomatic, peripheral striations and desquamative gingivitis–> Shiny red gums
Diagnosis of LP
isolated solitary lesions worrisome, candidiasis, microscopic hard due to look alikes, use direct immunofluorescence (fibrinogen at BMZ)
Treatment of LP
asymptomatic –> no treatment
Symptomatic –> antifungals, corticosteroids, immunomodulating agents
