Maxofacial Patho Part 2 Flashcards

1
Q

Cause of Tb

A

Mycobacterium tuberculosis, bacterial, less common than the other two

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2
Q

Canididiasis

A

Fungal disease, common

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3
Q

number of deaths from tb

A

2-3 million per year, particularly immunosuppressed; increasing in foreign born (unmonitored)

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4
Q

Infection of Tb

A

DOES NOT mean active disease; most that get active disease are simply immunosupressed

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5
Q

where tb effects

A

pulmonary of course, also extrapulmonary (skin-lupus vulgaris and Cervical Lymph nodes-scrofula)

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6
Q

Scrofula

A

tb in cervical ln

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7
Q

lupus vulgaris

A

skin tb

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8
Q

% of people with active oral tb and what is

A

.5-5%; non healing ulcerus

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9
Q

PPD test

A

skin test for tb, concern when one goes from negative to positive

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10
Q

Ways to diagnose tb

A

PPD, Sputum Culture, Histopathology

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11
Q

Microscopic features of Tb

A

formulation of granulomas-Caseating granuloma-wall of from the body

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12
Q

Caseating Granulomas

A

in pulmonary Tb-multinucleated balls of macrophages

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13
Q

Langhans Giant cells

A

Tb

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14
Q

Treatment

A
  • Multi-drug therapy
  • MDR-TB
  • XDR-TB (extremely resistant to everything)
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15
Q

MDR TB

A

Multi-Drug Resistance

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16
Q

Moniliasis

A

Candidiasis-Dimorphic fungus

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17
Q

Dimorphic fungus

A

yeast form-innocuous

Hyphal form-disease causing

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18
Q

Percentage of population with candidiasis

A

Common, in elderly, under dentures, not always disease causing

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19
Q

Forms of Candidiasis

20
Q

Psudeomembranous

A

“thrush” white/yellow plaque-red; removable; common in children and geriatric patients

21
Q

erythematous

A

Redness; baldness of tongue (lack papilla); scalded symptom (burned tongue)

22
Q

central papillary atrophy

A

on dorsal surface of tongue- loss of texture in middle of tongue in circle shape-old name is median rhomboid glossitis

23
Q

chronic multifocal

A

many places in the mouth; central pappillary and palate

24
Q

angular cheilitis

A

fungal infection at the corner of the mouth

25
denture stomatitis
under the dentures; often asymptomatic
26
Hyperplastic
candidiasis-invade epithelium- Will NOT rub off; byproducts are known carcinogens ; topical medications will not work due to penetration
27
Thrush
psuedomembranous candidiasis; resembles cottage cheese
28
resembles cottage cheese/curdled milk
thrush, or psuedomembranous candidiasis
29
stromatopyrosis
burning mouth, thrush
30
Stomatodynia
sore mouth; thrush
31
bald tongue
erythematous candidias
32
rhomboid glossitis aka central papillary atrophy location
@jcn of ant 2/3 and post 1/3 of dorsal tongue
33
Cause of median rhomboid glossitis
NOT developmental; caused by candidias; do not treat; triangular loss of pappila
34
Candidiasis that will not rub off
chronic hyperplastic-use systemic antifungals
35
therapeutic diagnosis
treat without confirming organism; retrospectively note if you were correct
36
Flourhexidine
Use commonly for perio diseases and candidiasis
37
Topical or oral for candiadis
topical common; use systemic anti fungal when needed
38
Double stranded DNA viruses
Herpes
39
HHV-1
recurrent, travels in nerve ganglia in latent state
40
reactive HHV
traumas (UV, hormones, illness)
41
Asymptomatic shedders
shed the virus for 24hrs at a time without showing symptoms-70% of people do
42
Site Specific
Recurrent lesions found on vermillion border, attached gingiva (keratinized and to bone), and hard palate (keratinized and to bone)
43
differentiate ulcerus/canker sore cores from HHV
canker sores-everywhere except gingiva an d hard palate (where HHV is)
44
Tzanch cells
in recurrent herpes simplex; virus travels down the nerve to epithelium; destroys connection between adjacent cells; these cells float around in the blister fluid; these are tzanch cells
45
Diagnosis of Recurrent herpes simplex
clinical; or serological (detect antibodies) which is less common