Oral Dysplasia and cancer cases Flashcards
38 years old
Risk factor - topical tobacco (snuff)
Otherwise fit and well
Thickened keratotic lesion, red patches, red spots
Biopsy - benign
Recommendation - stop smoking, regular review
64 year old
Unaware of the lesion left commissure
Risk factors - 20 cigs a day since 16 yrs, 10 pints beer per week, eats processed foods with little fresh fruit and vegetables.
Keratotic lesion (thickened in appearance), painless, very speckled.
Biopsy - Candidal leukoplakia
Treatment - Systemic antifungals,
Second biopsy - Squamous cell carcinoma
Treatment - Surgical excision with a margin of 1cm of normal tissue , 5 yr follow up review.
32 yr old
Left sided tongue white patch
Risk factors - smoker 10 a day since 18 yrs
1 bottle of vodka per week
White patches, red patches.
Biopsy - severe dysplasia (lesion will all become cancerous if not excised)
Treatment - excision with 5 mm normal tissue, smoking cession, alcohol reduction, long-term regular follow up.
47 yr old
Multiple white patches
Asymptomatic
Risk factors - none identified
Mapping biopsies
Close clinical follow up
Self examination
78 yrs old
Multiple white patches: bilateral buccal mucosa, lower right gingivae, right soft palate.
Mapping biopsies
Moderate to severe dysplasia
Treatment excision of lesions with 5mm normal margin
58 yr old
asymptomatic
white patch lingual alveolus FOM (“ebb and tide” pattern)
risk factor - binge drinker
Biopsy: Severe dysplasia
Treatment: Excision with a perimeter of 5mm normal tissue, follow up, repeat biopsy, risk factor reduction
(second biopsy after 1 year as a follow up)
73 yrs
Long history of lace like white patches inside both cheeks
not symptomatic
Risk factors - none identified
Lichen planus (potentially malignant condition)
Investigation - incisional biopsy
52 yrs
painful left cheek for several months
former smoker, stopped 6 year before was 15 cigarettes per day since age 20 yrs
Lichenoid reaction in the mouth (shouldn’t be confused with a lichen planus) as a result of amalgam restorations.
54 yrs
20 year history of oral white patches bilateral; buccal mucosa and left soft palate onto hard palate
Risk factors - alcohol <10 units per week
Thick, keratotic lesion, indurated margins
62 yr old, rheumatoid arthritis (taking strong immunosuppressants) and Sjorgrens syndrome.
Asymptomatic white patch right lateral tongue
No risk factors
Striated pattern
Hairy leukoplakia (can be associated with HIV)
65 yr painless lesion on right side of the tongue
unknown duration
Smoker 20 a day for 40 years
alcohol 4 bottles of wine per week
Indurated, squamous cell carcinoma, large
78 yrs old, asymptomatic white patch on the left gingivae in the LL5 and LL6 region, found by his own dentist on routine examination.
No risk factors
Medically - well controlled hypertension with amlodipine and statins.
Heterogenous patches
73 yr old, lesion on right side of tongue
Patient noticed an ulcer 6 weeks previously
not painful
noticed a lump in the right neck for the past month not painful
risk factors - none identified
White patch with red speckles, heat thick white patch, exophytic (growing out the way)
34 yr old, vague right side jaw and neck pain
present for 6-7 months
her glands were up and had not come down for a few months
the dentist suggested that her symptoms were due to her impacted wisdom teeth
medically she was fit and well, never smoked and consumed less than 10 units of alcohol per week.
Cancer
Treatment for cancer