Oral disease Flashcards
Oral ulceration?
Discontinuity in oral mucosa
Solitary ulcer?
Trauma (physical or chemical)
Malignancy (oral squamous cell carcinoma)
Infective (TB, tertiary syphilic)
Multiple ulcers?
most common cause
RAU (recurrent aphthous ulceration)
Usually well - no systemic disease
Exclude iron deficiency & GI disease
Major, minor, herpetiform
Minor aphthous ulcers?
Most common
<10mm
Heal within 14 days, no scarring
Rarely affect dorsum tongue or hard palate
Major aphthous ulcers?
> 10 mm
Weeks/ months
Heal with scarring
Bechets?
Multisystem condition
Hereditary systemic vasculitis (inflammation of blood vessels)
Almost identical ulcers to RAU
+ Genetic ulceration, uveitis, erythema nodosum
Anaemia?
Mucosal pallor Oral ulceration Glossitis (inflammation of tongue) Angular chellitis Predisposition to candida Disturbed taste
Other causes of multiple ulcers?
Mucocutaenous disorders
- Lichen Planus
- Lupus erythematous
- Vesiculobullos disease (pemphigus and pemphigoid)
Lupus erythematosus?
Discoid or systemic (AI)
Ulceration
White patches, red and white
Similar appearance to lichen P
Vesiculobullos disease - pemphigus vulgaris?
Oral manifestations 1st
Painful, extensive oral ulcers
Preceded by blisters
Nikolsky sign
Vesiculobullos disease - pemphigoid?
Autoimmune
Blisters
Painful oral ulceration
Affects mucous membranes of other organs e.g. eyes
What are oral manifestations of GI disease due to?
Underlying malabsorption & consequent haematinic deficiency
Gi diseases with oral manifestations?
Crohn’s
UC
Peutz jeghers
Gardners syndrome
Oral manifestations of Crohn’s?
May precede abdominal symptoms Cobble-stone mucosa Localised mucogingivitis Linear ulceration Tissue tags/ polyps Diffuse swelling (lips) Pyostomatitis vegetans
Pyostomatitis vegetans?
Erythema and oedema of the mucosa and numerous small, superficial yellow pustules
Oral manifestations of UC?
Oral ulceration
Pyostomatitis vegetans
Angular stomatitis
Reflects UC severity