Oral/Dental Health & Nutrigenomics Flashcards
What is nutrigenomics?
Understanding the interactions between the environment, genetics, and disease. Study of how our genetic makeup and metabolic makeup relate to our physiological response to various food compounds.
The goal of nutrigenomics is to ________ nutritional programs resulting in:
- ________
- ________
- ________
Develop
- Prevention
- Delaying
- Treatment of Diseases
Concept of Nutritgenomics Builds on the Premises that:
- Diet and dietary components can alter risk of _______ ________
- Food components can act on the human _________
- Diet could potentially compensate for or accentuate the effects of _____ polymorphisms.
- The ________ of diet depend on the balance of health, disease states, and on the individual’s background.
- disease development
- Genome
- Genetic
- Consequences
- susceptible host or tooth surface
- microorganisms such as streptococcus or lactobacillus in the dental plaque or oral cavity
- fermentable carbohydrates in the diet, which serve as the substrate for bacteria
- Time in the mouth for bacteria to metabolize the fermentable carbohydrates, producing acids and cause a drop in salivary pH to less than 5.5
are the
four elements needed to produce dental carries
Foods that contain fermentable carbohydrates, which when in contact with microorganisms in the mouth can cause stimulation to begin caries process are _________
Cariogenic
Foods that do not contribute to decay, are not metabolized by microorganisms, and do not cause a drop in salivary pH to 5.5 or less within 30 minutes are _______
Cariostatic
Eggs, fish, meat, and poultry, most vegetables, fats and sugarless fumes are examples of ______
Cariostatic foods
What is the term for dry mouth caused by inadequate saliva production?
xerostomia
What is the term for inflammation of the oral mucosa, causing severe pain and ulceration of the gingiva, oral mucosa, and palate causing eating to be painful?
Stomatitis
Plaque in atherosclerosis contains ________
Triglycerides
Individuals who are considered very high risk should have an LDL of _______mg/dL
<70 mg/dL
What is the total percentage of fat someone should have per day?
25-35%
Total cholesterol is made up of __________
HDL, LDL, Triglycerides
What is an inflammatory marker in CVD?
Fibrinogen
Normotension is recognized by what values?
120/80
Risk for CVD can be decreased with high ______
HDL cholesterol
What type of fat decreases LDL cholesterol?
Monounsaturated
What is the recommended saturated fat by TLC diet?
7% of total cals
What is the desirable level for HDL?
> 40 mg/dL
What is a food that is rich in monounsaturated fat?
avocadoes
What is a medical condition in which person is short of breath, retains fluid?
CHF, Congestive Heart Failure
What is the primary diet for people with CHF?
low sodium
Patient w/high cholesterol consumes a diet emphasizing ______ _____
saturated fats
How many mg of sodium in 1 tsp of salt?
2400mg
stress, smoking, inactivity, diet are _______ risk factors
modifiable
diabetes, metabolic syndrome, obesity are _____ risk factors
controllable
What is the term for excessive thirst?
polydipsia
T1 DM has an absolute deficiency of _____
insulin
What is not a symptom of heart failure?
bloated abodmen
What is not excluded from the dash diet?
Dairy
What mineral is not featured in dash? The minerals featured include potassium, magnesium and calcium
Cl
What is HTN criteria?
140/90
What is included in metabolic syndrome?
intrabdominal obesity
AMA recommendation for Hemoglobin A1C is less than ______
<7%
Recommendation from trans fatty acids by TLC is ______
0 or as low as possible
What is the term for excessive urination?
polyuria
Term for impaired glucose motility is ______
gastroparesis
What is hypoglycemia followed by rebound of hyperglycemia?
Somogyi effect
What are the risk factors for T2 DM?
genetic + environmental factors
What is one treatment for DKA?
Electrolyte replacement
This is not a ketone body
acetyl coA
Ketones bodies are produces as a result of what?
Fat breakdown
What macronutrient aids slow down of glucose levels?
Protein
Preprandial plasma glucose levels recommended by ADA are ______
80-130 mg/dl
Peak post prandial plasma glucose levels recommended by ADA is ______
<180
Element that can create a susceptible tooth for dental carries?
Acidic Saliva
What is the microorganism needed to ferment carbs to form dental carries?
Streptococcus mutans
pH level needed for pH level to drop down for oral bacteria to begin the metabolism process is
5.5
What is considered anticarigenic
xylitol
What isn’t a carciogenic causing food?
carrots
What is a cariostatic food
egg
what practice promotes dental carries
snacking on carciogenic foods
nutrigenomics will not
cure
- liquids clear quickly
- sticky foods that adhere to teeth/between
- chews that stimulate saliva flow
- high fiber/fat/protein w/no or little fermentable cho are cariostatic
- length of exposure
- dairy buffer acid
- nuts high fat, & fiber
are all factors of
cariogenicity
- modify fermentable CHOs
- Brush, rinse, chew sugarless gum (15-20 min)
- Snack on cariostatic foods
- avoid carbonated beverages
- floss twice daily
- use fluoridated toothpastes, gels, rinses
are al ways to take care of
your teeth
anticariogenic foods prevent plague and include
xylitol, sugarless gum, and aged cheese
- grains
- fruits
- dairy
- sugary beverages
- sweets
are carcinogenic foods