Oral Cancer Flashcards

1
Q

what is oral sub mucous fibrosis

A

chronic, progressive oral potentially malignant disorder associated with betel quid/ Areca nut

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2
Q

how does oral sub mucous fibrosis present clinically

A

pale coloured mucosa, firm to palpate

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3
Q

what is epithelial dysplasia

A

cytological epithelial changes resulting from accumulation of genetic alterations, usually arising in a range of oral potentially malignant disorders and indicating a risk of malignant transformation to squamous cell carcinoma

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4
Q

epithelial dysplasia grading

A

mild
moderate
severe

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5
Q

differential feature of dysplasia compared with oral squamous cell carcinoma

A

in dysplasia the atypical cells are confined to the surface epithelium

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6
Q

management of epithelial dysplasia

A

modify risk factors
anti fungal tx
excision

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7
Q

what percentage of oral cancers are squamous cell carcinoma

A

over 90%

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8
Q

does oral cancer have a screening programme

A

no

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9
Q

risk factors for oral cancer

A

tobacco
alcohol
betel quid
previous oral cancer
UV light exposure
poor diet
immune suppression
oral potential malignant disorders

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10
Q

High risk sites for oral cancer

A

lateral/ventral tongue
floor of mouth
retromolar trigone

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11
Q

signs and symptoms of oral cancer

A

lumps
ulcers
white patches
red patches
speckled patches
non healing socket
tooth mobility - not perio
induration of mucosa
dysphagia
pain/ paraesthesia
bleeding

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12
Q

additional detection tests

A

toluene blue
autofluorescence

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13
Q

referral guidelines for suspected cancer

A

persistent and unexplained head and neck lump > 3 weeks
unexplained ulcer or swelling/ induration > 3 weeks
red or mixed red and white patch > 3 weeks
persistent hoarseness > 3 weeks
persistent pain in throat > 3 weeks

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14
Q

when should an appointment be made for suspected oral cancer - time like how many weeks

A

an appointment in 2 weeks

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15
Q

how is diagnosis of oral squamous cell carcinoma confirmed

A

biopsy

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16
Q

how is squamous cell carcinoma graded

A

by degree of differentiation

17
Q

tx for oral cancer

A

surgery
+/- adjuvant therapy
monoclonal antibodies

18
Q

classification of malignant tumours

A

TNM staging

19
Q

TNM components

A

T - extent of primary tumour
N - regional lymph node metastasis
M - distant metasis

20
Q

the higher the number the more extensive or less extensive the diseae

A

the higher the number the more extensive the disease

21
Q

core data items included in pathology report

A

maximum dimension of tumour
tumour type
tumour grade
depth of invasion
pattern of invasive front
bone invasion
perineurial invasion
lymph-vascular invasion

22
Q

core data items for neck dissection specimens

A

total number of lymph nodes at each anatomical level
number of nodes involved in metastatic carcinoma
size of largest metastatic deposits
extra capsular spread
pathological staging