optical isomerism Flashcards

1
Q

what is an optical isomer

A

A molecule with a non-superimposable mirror image

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2
Q

what is a chiral carbon

A

a carbon with 4 different groups attached to it

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3
Q

what does a polariser do

A

only lets some light through

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4
Q

what will optically active samples do to plane-polarised light

A

optically active samples will rotate plane -polarised light

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5
Q

what is a racemic mixture

A

a mixture containing equal amounts of each other therefore they don’t have optical activity since the enantiomers effects cancel each other out

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6
Q

how do racemic mixtures form

A

1- nucleophilic addition to carbonyls
2- electrophilic substitution in alkenes

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7
Q

what do the two enantiomers of thalidomide do

A

1- alleviates nausea and morning sickness
2- causes birth defects

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8
Q

what is the importance of enantiomers in enzymes

A

actives sites are specific shapes therefore a substrate needs a specific spatial arrangement to bond to the matching area of active site

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