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Neuro II Exam 1 > Opthalmologic Agents - Linger > Flashcards

Opthalmologic Agents - Linger Flashcards

1
Q

ocular route admin

A

topical

into inferior fornix of conjunctiva aka inferio cul de sac

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2
Q

nasolacrimal drainage

A

contribute to systemic absorption

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3
Q

esterase

A

metabolize prodrugs

esters cleaved that are more soluble

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4
Q

contraction of pupil

A

M3 receptor

miosis

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5
Q

dilation of pupil

A

alpha1 receptor

mydriasis

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6
Q

accomodation

A

ciliary muscle

beta 2 and M3 receptors

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7
Q

anisocoria

A

inequal pupil

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8
Q

sympatetic tract damage

A

horners syndrome

ptosis, miosis, anhydrosis

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9
Q

CN 3 palsy

A

dilated unreactive pupil

no miosis**

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10
Q

adies pupil

A

damage to PS tract

mydriasis, sweating, loss of DTR

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11
Q

supersensitive to pilocarpine

A

muscarinc agonist

adies pupil

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12
Q

cocaine and horners

A

no dilation of pupil

-indicate damaged sympathetics

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13
Q

opiod agonist

A

excite PS nerves
-mu receptor

get pinpoint pupils

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14
Q

side effects of sympathomimetics

A

photosensitivity, conjunctival hyperemia hyper sensitivity

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15
Q

phenylephrine

A

sympathomimetic

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16
Q

cocaine

A

sympathomimetic

17
Q

hydroxyamphetamine

A

sympathomimetic

18
Q

evaluation of anisocoria

A

hydroxyamphetamine

19
Q

timolol

A

beta antagonist

20
Q

tx of glaucoma

A

timolol

21
Q

normal vs. adies pupil

A

normal has constriction with high dose pilocarpine

adies has constriction with low dose pilocarpine

22
Q

glaucoma

A

increased IOP

closed and open angle

23
Q

mechanism of latanoprost

A

increased outflow of aqueous humor

24
Q

prostaglainds

A

latanoprost

25
Q

decreased aqueous humor production

A

beta blockers
CAIs
alpha2 agonists

26
Q

increased aqueous humor outflow

A

prostaglandin F2a analog
alpha-adrenergic agonist - nonselective
parasympathomimetics

27
Q

beta blockers

A

decreased aqueous production

28
Q

first line for glaucoma

A

latanoprost

prostaglandin F2a analog

29
Q

non-selective prodrug of epinephrine

A

dipivefrin

lowers IOP in glaucoma

30
Q

apraclonidine

A

selective a2 agonist - does not cross BBB

31
Q

dorzolamine and brinzolamide

A

topical CAIs

inhibit CA - reduced bicarb formation - reduced fluid transport

reduce IOP in glaucoma

32
Q

oral CAI

A

acetazolamide

33
Q

adverse of steroid

A

fam hx of glaucoma

-steroid induced IOP in crease - may occur 90% patients

Neuro II Exam 1 (14 decks)

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