opthalmic drugs Flashcards
what do parasympatholytic agents do to iris
constrict
what do symphathomimetics do to iris?
dilate
examples of parasympatholytic agents (2)
- Tropicamide
2. cyclopentolate
do sympathomimetics affect accomodation?
no
example of sympathomimetic (1)
phenylephrine
does tx of viral conjunctivitis include antivirals?
no antivirals ineffective against adenovirus
risk assc’d with use of topical steroids in tx of HSV?
- can exacerbate herpes keratitis,
- elevate IOP,
- cause cataracts
which PG analogue is preservative free?
tafluprost
how do PG analogues fxn for glaucoma?
incr uveoscleral outflow
how are beta adrenergic blockers effective for glaucoma?
decr aqueous production
which people should not be tx’d with beta antags?
asthma
COPD
which drug incr aqueous outflow thru trabecular meshwork
cholinergic agonists
what is the safest glaucoma medicine for a pregnant woman
brimonidine (adrenergic agonist)
which drug can cause apnea in children
brimonidine
if you give systemic meds above recommended doses, are ocular SE likely to be reversible or irreversible?
reversible
if you give systemic meds at recommended doses, are ocular SE likely to be reversible or irreversible?
can be irreversible or reversible
floppy iris syndrome
Alpha 1 blockers
cornea, retina, ON
tamoxifen
dose related optic neuropathy
ethambutol
corticosteroids can lead to
cataracts, glaucoma
irreversible maculopathy
Chloroquine/hydroxychloroquine
insidious onset often bilateral nonarryhtmic anterior ischemic optic neuropathy that is irreversible; and corneal changes that are reversible
amiodarone
acute angle closure glaucoma irreversible SE
topiramate
HMG coa reductase inhibs reversible SE
myopathy, diplopia, ptosis, ophthalmoplegia, cataracts
what drug can cause reversible blue color tinge
PDE5 inhibs
which drugs can result in ocular SE above recommeded doses (3)
- digitalis
- diphenhydantoin
- thioridazine
Corneal/lens opacities
chlorpromazine
