1
Q

50% of all blindness is due to

A

Cataracts

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2
Q

Vit A function? Get from?

A

Immune system
Production of Rhodopsin

Animal produce and green leafy veg

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3
Q

Vit A blindness is often very rapid and occurs when?

A

Sudden demand on Vit A stores - Eg during infection

*Should always give Vit A in malnourished kids with pyrexial illness [Especially Measles / diarrhoea]

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4
Q

Vit A blindness is often very rapid and occurs when?

A

Sudden demand on Vit A stores - Eg during infection

*Should always give Vit A in malnourished kids with pyrexial illness [Especially Measles / diarrhoea]

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5
Q

Vit A deficiency replacement

A

IM on days 1,2, 14
200k IU if >1yr

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6
Q

Main infection-> blindness? Reservoir and spread?

A

Chlamydia Trachomatis
Reservoir is copious discharge from others with the disease
-Either then contact with hands / clothes
-Eye seeking flies - Musca domestica / Musca sorbens

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7
Q

What happens in trachomata eye disease

A

Chronic repeated infection (as you don’t develop immunity)
-> keratoconjunctivitis
-> conjunctival Scar formation
-> turns eye lids inwards (entropion)
-> Eye lashes then abrade globe (trichiasis)
-> chronic keratitis and scaring + lots of secondary infections

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8
Q

Seen on underside of upper eyelid in early trachomata disease?

A

Little white follicles
vascular proliferation

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9
Q

Rx of trachomata eye disease?

A

SAFE strategy

Surgery for inturned lashes
Azithromycin (concentrated in tears)
Face washing - reduces reservoir and reduces fly attraction
Environmental improvement

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10
Q

3 key ways leprosy affects eyes? which type of leprosy?

A

Direct invasion
-May get mass at the limbus (leproma)
-iris which produces white discrete particles

Type -1 reactions
-Inflammation of CN V / VII -> irreversible palsy.
-Paucibacilliary (PB) or Multibacilliary (MB) leprosy

Type 2 reactions (erythema nodosum leprosy)
-recurrent iritis / sceritis -> glaucoma / cataract
-MB leprosy only

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11
Q

Bar invading eye directly how might face lepsoy cause blindness?

A

Facial palsy
-> incomplete closure of lids + anaesthetic cornea
-> chronic keratitis and scaring

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12
Q

Chronic iritis in leprosy appearance?

A

Very small constricted pupil (unopposed action of constrictor)

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13
Q
A

Cerebral malaria
white-centred haemorrhages, a superficial blot haemorrhage at the fovea, mild macular whitening (black arrow) and cotton wool spot (white arrow)

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14
Q
A

ocular toxoplasmosis

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15
Q
A

Ocular toxoplasmosis

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16
Q
A

ocular CMV

17
Q
A

Ocular CMV

18
Q

Why high rates of cataracts in chronic leprosy

A

frequent steroid use

19
Q

What happened here in B? pt has leprosy

A

Lagophthalmos - the inability to close the eyelids normally
[due to facial nerve palsy from leprosy]