Opioid Stewardship Flashcards
What are the aims of chronic pain management?
To improve understanding of pain, reduce central sensitisation and pain intensity, improve social, emotional and physical function
What is the first line management for chronic pain?
social interventions, cognitive behavioural therapy, sleep and physical activity
What is the second line treatment for chronic pain?
analgesics, invasive procedures
Describe substance use disorder.
social, psychological and physiological phenomenon affecting ability to control substance use, determined by patters of misuse
What makes opioids high risk?
combination of addictive and toxic properties
What are some common medications used in opioid replacement therapy?
buprenorphine and methadone
What is the aim of opioid replacement therapy?
alleviate opioid cravings with minimal SEs
Methadone MOA
full opioid mu receptor agonist
buprenorphine MOA
partial opioid mu receptor agonist
Describe morphine milligram equivalents
calculation to convert doses to standard measure when changing between opioids to account for relative potency differences
list some regulatory responses to the opioid crisis
post op prescribing restrictions, codeine rescheduling, prescription drug monitoring programs
List the signs of opioid OD
sedation, falling asleep constantly, slow response to stimulus, slow and shallow breathing, pale, blue and cold skin
Naloxone MOA
competitive inhibitor of mu receptor
what routes can naloxone be given?
IM, nasal spray
WHat is the main consideration when administering Naloxone?
when administering to unconscious px consider rapid withdrawal
