Hormone System Therapeutics

Question 1

What drugs can hypothyroidism effect activity/toxicity of?

Answer 1

sedatives and anticoagulants

Question 2

what does increased TSH indicate?

Answer 2

thyroid deficiency as thyroid is not converting TSH into T3/T4

Question 3

List treatment options for hyperthyroidism

Answer 3

carbimazole, propylthiouracil, radiotherapy, surgery

Question 4

list medication used for hypothyroidism

Answer 4

levothyroxine

Question 5

describe steroids

Answer 5

characterised by structure of 17 carbon atoms, wide reaching effects on body, designed to mimic and produce effects of specific steroid hormones in body, most commonly reduce inflammation

Question 6

corticosteroids
MOA

Answer 6

mediate activity of glucocorticoid receptors, leading to effects such as decreased inflammation, altered BGL, suppressed immune system

Question 7

prednisone
indication:

Answer 7

autoimmune/inflammatory, acute asthma/COPD flare up, acute gout, croup

Question 8

when would mini-pill be recommended over combined oral contraceptive?

Answer 8

mini-pill recommended if COC is contraindicated (CVD risk, clots, migraines etc)

Question 9

COC
MOA

Answer 9

inhibit ovulation, reduce endometrial receptivity to implantation, thickens cervical mucous

Question 10

mini pill
MOA

Answer 10

inhibit ovulation, thickening of cervical mucous