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Pharm 1 > Opioid Analgesics > Flashcards

Opioid Analgesics Flashcards

1
Q

codeine sulfate MOA

A

opioid agonist

binds to opioid receptors

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2
Q

codeine sulfate indications

A

opioid analgesic- pain

antitussive

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3
Q

codeine sulfate contraindications

A

peds, pregnant, laboring, breastfeeding moms

asthma, resp insufficiency, apnea, paralytic ileus

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4
Q

codeine sulfate AE/SE

A

N/V

Opioid SE- hypotension, bradycardia, sedation dizzy, constipation, urinary retention, resp. distress

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5
Q

codeine sulfate interactions

A

other CNS depressants=

alcohol, antihistamines, barbiturates, benzos

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6
Q

codeine sulfate nursing considerations/education

A 
high abuse potential
Tylenol #3- codeine and Tylenol- don't take more Tylenol  
no benzo's
monitor resp, CNS depression, vital signs etc. 
only agonist w/ ceiling effect
have naloxone ready 
fall risk 
monitor urinary retention
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7
Q

fentanyl (Sublimaze) MOA

A

opioid agonist

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8
Q

fentanyl (Sublimaze) indications

A

pain- very potent analgesic

sedation/general anasthesia

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9
Q

fentanyl (Sublimaze) admin

A

transdermal patch- chronic pain
IV- RAPID onset
.1mg= 10g of morphine

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10
Q

fentanyl (Sublimaze) contraindications

A

sub abuse
asthma, resp insufficiency, apnea, paralytic ileus
pregnancy

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11
Q

fentanyl (Sublimaze) SE/AE

A

HIGH abuse potential
normal opioid SE- hypotension, bradycardia, sedation dizzy, constipation, urinary retention, resp. distress
sedation- which may be desired

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12
Q

fentanyl (Sublimaze) nursing considerations/education

A 
high abuse potential 
monitor vital signs
have naloxone ready 
no Benzo's 
fall risk 
monitor urinary retention 
have naloxone ready
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13
Q

morphine sulfate (MSIR/Roxanol) MOA

A

opioid agonist

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14
Q

morphine sulfate (MSIR/Roxanol) admin

A

oral, IM, IM, rectal

epidural

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15
Q

morphine sulfate (MSIR/Roxanol) indications

A

severe pain

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16
Q

morphine sulfate (MSIR/Roxanol) contraindications

A

renal impairment
after biliary surgery- induces spasm of the sphincter of oddi
asthma, resp insuff., apnea, paralytic ileus
pregnancy

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17
Q

morphine sulfate (MSIR/Roxanol) SE/AE

A

resp depression, sedation, N/V, constipation, urinary retention, bradycardia, hypotension

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18
Q

morphine sulfate (MSIR/Roxanol) interactions

A 
alcohol
antihistamines
barbiturates
benzos 
other CNS depressants
MAOIs
st john wart
19
Q

morphine sulfate (MSIR/Roxanol) nursing considerations/education

A 
high potential for abuse 
tolerance/cross sen w other opioids
monitor vitals
fall risk 
monitor urinary retention
20
Q

oxycodone (OxyIR/Percocet) MOA

A

opioid agonist- structurally related to morphine

21
Q

oxycodone (OxyIR/Percocet) indications

A

pain- analgesic

22
Q

oxycodone (OxyIR/Percocet) contraditions

A

if taking percocet= do not take more tylenol

asthma, resp insuff., apnea, paralytic ileus, pregnancy

23
Q

oxycodone (OxyIR/Percocet) SE/AE

A 
N/V
hypotension
bradycardia
sedation
dizzy/drowsy
urinary retention/ constipation 
resp. depression
24
Q

oxycodone (OxyIR/Percocet) interactions

A 
alcohol
antihistamines
barbiturates
benzos 
other CNS depressants
25
Q

oxycodone (OxyIR/Percocet) nursing considerations/education

A 
percocet- no more Tylenol 
no benzos
monitor vitals, urinary retention/bowel fx
fall risk
normal opioid considerations
26
Q

acetaminophen (tylenol) MOA

A

non-opioid analgesic

COX inhibitor limited to CNS

27
Q

acetaminophen (tylenol) indications

A

mild-mod pain

fever

28
Q

acetaminophen (tylenol) contraindications

A

liver disease-hepatotoxicity

alcoholism

29
Q

acetaminophen (tylenol) AE/SE

A

hepatotoxicity

30
Q

acetaminophen (tylenol) interactions

A

liver disease
alcohol
warfarin

31
Q

acetaminophen (tylenol) dosing

A

FDA= no more than 4000mg/day
manufacter= no more than 3000mg/day
liver disease= no more than 2000mg/day

32
Q

acetaminophen (tylenol) nursing considerations/education

A

antidote- acetylcysteine

keep track of dosing per 24 hours

33
Q

tramadol (Ultram) MOA

A

non-opioid misc. analgesic

binds to opioid receptors, blocks reuptake of norepinephrine and serotonin

34
Q

tramadol (Ultram) indications

A

mod.- severe pain

35
Q

tramadol (Ultram) contraindications

A

not for patients over 75
intoxication
under 12 yrs old

36
Q

tramadol (Ultram) AE/SE

A

similar to opioids
drowsy, dizzy
reduces seizure threshold**

37
Q

tramadol (Ultram) interactions

A

MAOIs

SSRIs, tricyclic antianxieties

38
Q

tramadol (Ultram) nursing considerations/ education

A

measure baseline vitals
not for patient over 75 yrs old
monitor seizure threshold

39
Q

naloxone (Narcan) MOA

A

opioid antagonist

blocks opioid receptors

40
Q

naloxone (Narcan) indications

A

reverse opioid oversdose

41
Q

naloxone (Narcan) contraindications

A

not effective on non-opioid drugs,

42
Q

naloxone (Narcan) AE/SE

A

ventricular arrhythmias, HR/ resp rate incr. abstinence syndrome

43
Q

naloxone (Narcan) nursing education/ cosniderations

A

duration of action 1-2 hrs

if giving post-op be prepared w/ alternative analgesic

Pharm 1 (7 decks)

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