Module 2- general info Flashcards

1
Q

types of antibiotic therapy

A

empiric, definitive, prophylactic, therapeutic, subtherapeutic, superinfection

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2
Q

types of bacteria

A

bacilli- rod
cocci-round
gram -
gram +

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3
Q

gram + bacteria

A

2 layer cell wall that is easy to penetrate

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4
Q

gram - bacteria

A

3 layer cell wall = more difficult to penetrate

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5
Q

mycobacterium

A

special bacteria, waxy cell wall, harder to kill

mycobacterium tuberculosis-

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6
Q

virus characteristics

A

reproduce inside cell
=effort to kill virus usually toxic to host
antibiotics are ineffective

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7
Q

fungi characteristics

A

plant like organisms that don’t need to survive
primary fx is to eat dead tissue
treat with antifungals

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8
Q

parasite characteristics

A

may live in host cells, organs, structures

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9
Q

helminths

A

worms that live in intestines

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10
Q

example of parasitic infection

A

malaria

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11
Q

aerobic bacteria

A

require oxygen to survive

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12
Q

aerobic bacteria usually found in

A

mouth, GI, lungs

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13
Q

anaerobic bacteria

A

don’t need oxygen to survive

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14
Q

example of anaerobic

A

gangrene caused by clostridium perfringes

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15
Q

types of bacteria antibiotics

A

bactericidal and bacteriostatic

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16
Q

bactericidal antibiotics

A

kills bacteria directly by:
weakened cell wall =open and lyse
bind to ribosomes and dec. protein synthesis depleting replication; or kill directly

17
Q

bacteriostatic antibiotics

A

interfere w/ bacteria replication -> slows protein synthesis= gradually decreasing number of bacteria in system allowing immune system to kill remaining

18
Q

which antibiotics are beta lactams

A

penicillin’s and cephalosporines

19
Q

what type of antibiotics can cause antibiotic resistance?

A

broad spectrum antibiotics

20
Q

disinfectant

A

often kill organisms, only used on non-living objects

bactericidal

21
Q

antiseptic

A

applied to living tissue,

bacteriostatic

22
Q

antiretroviral therapy (ART)

A

reduces replication of HIV

interfere w/ life cycle of HIV retrovirus

23
Q

types of antiretroviral drugs

A

viral entry blockers

enzyme inhibitors

24
Q

viral entry blockers kinds

A

entry fusions inhibitors and CCR5 inhibitors

25
Q

entry fusion inhibitors

A

inhibit HIV disease that is advanced or resistant

26
Q

CCR5 antagonists

A

treat only HIV 1 which binds to CCR5- blocks fusions of HIV to CD4 cells

27
Q

enzyme inhibitors

A

nucleoside transcriptase inhibitors, integrase inhibitors, protease inhibitors

28
Q

viral replication

A

viruses can not replicate on own, must be attached and enter host cell (called fusion)

29
Q

viruses can enter body through 4 routes

A

inhalation to resp tract, ingestion GI tract, transplacental, inoculation- skin mucous membranes

30
Q

antitubercular drugs

A

reduce cough to reduce infectiousness

reduce s/s

31
Q

antifungal drug therapy treats

A

yeasts, molds

32
Q

yeasts

A

single celled fungus, reproduce by budding

33
Q

molds

A

multi- cellular, characterized by long, branching filaments (hyphae)

34
Q

HIV characteristics

A

intracellular parasitic virus, has genetic material used to reproduce in form of RNA rather than DNA
attacks CD-4 cells that play role in immune system

35
Q

2 forms of HIV

A
HIV 1 (worldwide)
HIV2 (common in west africa) and develops more slowly
36
Q

phases of retrovirus

A
  1. attachment/binding
  2. uncoating and fusion
  3. DNA synthesis
  4. integration
  5. transcription
  6. translation
  7. cleavage
  8. budding