Opiods

Question 1

Agonists; Major opioids

Answer 1

• Morphine: Resp dep, bronchoconstriction, vasodilatation, analgesic, bradycardie, hypothermia/tension
• Fentanyl: Anesthesia, high lipid solubility (potence)
• Pethidine: Biliary pancreatic colic pain , lower myocardial infracion
• Methadone: Opioid dependance treatment

Question 2

Agonists ; Minor oipoids

Answer 2

-Codeine:
Antitussive, Analgesic, Antidiarrheal
-Dextropropoxyphen: same as codeine
-Tramadol: Analgesic avoid in myocardial infraction and low risk of resp dep constipation ad urinary retention

Question 3

Partial agonists

Answer 3

-Buprenorphine: Opiod dependance treatment

Same as morphine with less cardiovascular effects

Question 4

Antagonists

Answer 4

• Naloxone: Respiratory depression treatment

- Naltrexone: Detoxification of opiods and alcohol