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pharmacology > Antimigraine and antihistamine > Flashcards

Antimigraine and antihistamine Flashcards

1
Q

Atimigraine treatment

A 
Paracetamol
NSAIDs
Minor opiates
Triptans
Ergotamine
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2
Q

Triptans

A

Agonist of 5-HT receptors

Vasoconstriction

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3
Q

Ergotamine

A

Vasoconstrictor of extracranial arteries

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4
Q

Preventive migraine treatment: Profylaxis

A
  1. Tricyclic antidepressants
  2. Beta blockers
  3. Methysergide
  4. Cyproheptadine
  5. Calcium antagonists
  6. Antiepileptics
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5
Q

Histamine release

A
  • Hypersensitivity reactions
  • Inflamatory reactions
  • Temperature changes
  • Secretion of gastric juice
  • Immune response
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6
Q

Antihistamine H1

A

1st generation: Cross BBB; sedation, very potent

2nd generation: Do not cross BBB, moderate effect

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7
Q

Antihistamine H1 indications

A
  • Allergies
  • Antimotion sickness
  • Sedatives/ Hypnotics
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