Opiods Flashcards
Name the opioid drugs that are classified as morphine like agonists
Oxycodone
Codeine
Hydrocodone
Hydromorphone
Oxymorphone
Name the opioid drug that are meperidine-like agonists (Phenylpiperidines)
Fentanyl
Name the opioid dug that’s methadone-like agonists (Diphenylpropylamines)
Methadone
Name the atypical opioid drugs
Tramadol
Tapentadol
Which opioids should not be prescribed for kids?
Morphine (codeine)
Tramadol
Which opioid agent increases risk for QTc prolongation?
Methadone
Name the metabolites for the morphine class drugs
M3G & M6G
(Morphine 3-glucuronide)
Metabolites M3G & M6G are at risk for causing what?
Renal failure
Which opioid would you prescribe for elderly patients or patients with renal impairment?
Hydromorphone
Which opioid would you prescribe to a patient who develops an allergy to other types of opioids or post-op shivers?
Meperidine
Which opioid is good for ICU patients who have cardiac issues ?
Fentanyl
How many routes can fentanyl be administered?
3.
- Transdermal
- Transmucosal
-Intranasal
What are the cons of using Methadone?
Difficult to titrate
QTc prolongation = Torsades de Pointes
Associated with addiction
What are the pro for using Methadone?
naturally long acting
useful in neuropathic pain (NMDA antagonists)
No toxic metabolites
Name the opioid agent that’s a partial mu agonists/kappa antagonists?
Buprenorphine
Name the drugs that are kappa agonists/mu antagonists
Pentazocine
Butorphanol
Nalbuphine
Which mixed agonists-antagonists opioid are used in OBGYN?
Nalbuphine
Name the drugs that are delta agonist/Mu antagonists
Dezocine
Which drugs are commonly used to reverse toxic effects of opioids?
Naloxone (Narcan)
Naltrexone
Nalmefene
Mehtylnaltrexone
Alvimopan
Naloxegol
Naldemedine
Which atypical opioid is recommended for moderate to moderately severe pain?
Tramadol
Which atypical opioid is recommended for moderate to severe pain?
Tapentadol
Which agent is the most effective in reversing respiratory depression?
Naloxone
