Opiods

Question 1

Name the opioid drugs that are classified as morphine like agonists

Answer 1

Oxycodone
Codeine
Hydrocodone
Hydromorphone
Oxymorphone

Question 2

Name the opioid drug that are meperidine-like agonists (Phenylpiperidines)

Answer 2

Fentanyl

Question 3

Name the opioid dug that’s methadone-like agonists (Diphenylpropylamines)

Answer 3

Methadone

Question 4

Name the atypical opioid drugs

Answer 4

Tramadol
Tapentadol

Question 5

Which opioids should not be prescribed for kids?

Answer 5

Morphine (codeine)
Tramadol

Question 6

Which opioid agent increases risk for QTc prolongation?

Answer 6

Methadone

Question 7

Name the metabolites for the morphine class drugs

Answer 7

M3G & M6G
(Morphine 3-glucuronide)

Question 8

Metabolites M3G & M6G are at risk for causing what?

Answer 8

Renal failure

Question 9

Which opioid would you prescribe for elderly patients or patients with renal impairment?

Answer 9

Hydromorphone

Question 10

Which opioid would you prescribe to a patient who develops an allergy to other types of opioids or post-op shivers?

Answer 10

Meperidine

Question 11

Which opioid is good for ICU patients who have cardiac issues ?

Answer 11

Fentanyl

Question 12

How many routes can fentanyl be administered?

Answer 12

3.
- Transdermal
- Transmucosal
-Intranasal

Question 13

What are the cons of using Methadone?

Answer 13

Difficult to titrate
QTc prolongation = Torsades de Pointes
Associated with addiction

Question 14

What are the pro for using Methadone?

Answer 14

naturally long acting
useful in neuropathic pain (NMDA antagonists)
No toxic metabolites

Question 15

Name the opioid agent that’s a partial mu agonists/kappa antagonists?

Answer 15

Buprenorphine

Question 16

Name the drugs that are kappa agonists/mu antagonists

Answer 16

Pentazocine
Butorphanol
Nalbuphine

Question 17

Which mixed agonists-antagonists opioid are used in OBGYN?

Answer 17

Nalbuphine

Question 18

Name the drugs that are delta agonist/Mu antagonists

Answer 18

Dezocine

Question 19

Which drugs are commonly used to reverse toxic effects of opioids?

Answer 19

Naloxone (Narcan)
Naltrexone
Nalmefene

Mehtylnaltrexone
Alvimopan
Naloxegol
Naldemedine

Question 20

Which atypical opioid is recommended for moderate to moderately severe pain?

Answer 20

Tramadol

Question 21

Which atypical opioid is recommended for moderate to severe pain?

Answer 21

Tapentadol

Question 22

Which agent is the most effective in reversing respiratory depression?

Answer 22

Naloxone