Opiates

Question 1

Term used for entire family of opiates including synthetic and semi-synthetic

Answer 1

Opioid

Question 2

An opioids is any agent that binds to opioid receptor found in

Answer 2

Central nervous system

Gastrointestinal track

Question 3

Morphine

Answer 3

Schedule I
Schedule II

Analgesic

Question 4

What are the two opioid receptors

Answer 4

Meu receptor –> respiratory depression, hypothermia, euphoria

K (kappa) receptor –> spinal analgesia, sedation

Gamma receptor (binding sites for most endogenous proteins) –> spinal analgesia, hallucinations

Question 5

Opiod’s are classified into three groups

Answer 5

Full agonist
Full antagonist
Mixed agonist

Question 6

Morphine derivatives

Answer 6

Codeine –> weak meu
Fentanyl –> strong meu
Heroin –> strong meu
Hydrocodone –> meu

Question 7

Goodness of fit

Answer 7

Degree of complement between receptor binding site and drug determines extent of analgesia and duration

Question 8

Color Test: Opiods

Answer 8

Marquis

Question 9

Color Test: Morphine

Answer 9

Mecke’s

Concentrated Nitric Acid

Question 10

Opiates are drugs derived from

Answer 10

Opium