Opiate OD

Question 1

Are opiod and opiate the same?

Answer 1

no

Question 2

What is an opiate?

Answer 2

naturally occurring (codeine/morphine)

Question 3

What is an opiod?

Answer 3

synthetically derived (fentanyl/oxycodone)

Question 4

What are possible DDx for opiate OD?

Answer 4

1. Hypoglycaemia

2. Head injury

Question 5

What bedside investigations are done for opiate OD?

Answer 5

1. CGB

2. ABG

Question 6

Why is a CBG done?

Answer 6

exclude hypoglycaemia

Question 7

Why is an ABG done?

Answer 7

assess for T2 resp failure and acidosis

Question 8

What lab tests are done for opiate OD?

Answer 8

1. Plasma paracetamol concentration – mixed OD?
2. FBC
3. U&E
4. LFT

Question 9

Why is FBC done?

Answer 9

exclude infectious aiteology

Question 10

Why is U+E done?

Answer 10

opioid accumulation due to renal impairment

Question 11

Why are LFTs done?

Answer 11

are they able to metabolise the opioid effectively? Acute liver damage?

Question 12

What imaging is done?

Answer 12

CT Head – if patient has altered mental status

Question 13

What is the early presentaiton of opiate OD?

Answer 13

1. Reduced consciousness
2. Respiratory depression (bradypnoea)
3. Miosis
4. Bradycardia, hypotension

Question 14

What is the late/serve presentation of opiate OD?

Answer 14

1. Low GCS

2. Coma

Question 15

What is the management for opiate OD?

Answer 15

IV Naloxone

Question 16

Why are these the presentations?

Answer 16

are all parasympathetic symptoms as opioids are CNS depressants