Opiate agonists

Question 1

How is diamorphine administered?

Answer 1

Parenteral

Question 2

How is methadone given?

Answer 2

Oral

Question 3

How is Pethidine given?

Answer 3

Oral and Parenteral

Question 4

How is Codeine given?

Answer 4

Oral and Parenteral

Question 5

What are the adverse reactions of Morphine?

Answer 5

Respiratory depression
Nausea and vomiting
Constipation
Difficulty in passing urine
Urticaria and Bronchospasm (due to histamine release)
Tolerance
Withdrawal reactions 
Dependence with repeated exposure

Question 6

What is the use of Morphine?

Answer 6

For moderate-to-severe pain and for acute heart failure (relieve pain and reduce anxiety, and dilates blood vessels)

Question 7

What is the use of Codeine?

Answer 7

Mild pain, diarrhoea and anti-tussive (cough suppression)

Question 8

What is the mechanism of action of Dextropropoxyphene? How is it different from Morphine, Methadone etc?

Answer 8

Opiate partial agonist.

Morphine and Methadone are opiate agonist, but Dextropropoxyphene is an opiate partial agonist.

Question 9

What type of drug is Tramadol?

Answer 9

a miu-opioid agonist

Question 10

What are the advese effects of Tramadol?

Answer 10

seizures, dependence, neusea, constipation

Question 11

How is Tramadol given?

Answer 11

Oral, IV, IM