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Drugs > Anti-cancer drugs > Flashcards

Anti-cancer drugs Flashcards

1
Q

What is the action of methotrexate?

A

Inhibits the synthesis of purines and pyrimidines by inhibiting DHFR (dihydrofolate reductase).

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2
Q

What substance can reverse the effects of methotrexate?

A

Folinic acid

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3
Q

What is the severe but rare side effect of cyclophosphamide?

A

Cystitis

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4
Q

What is the rare side effect of doxorubicin

A

cardiotoxicity

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5
Q

What are the occasional side effects of Methotrexate?

A

Liver and kidney toxicity and skin rash

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6
Q

What is the action of Vincristine?

A

Binds to tubulin binders and prevent mitosis

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Drugs (10 decks)

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