Ophthalmology Conditions Flashcards
Dry eye syndrome can result from a deficiency in? (3)
Any of the three components of the tear film i.e.:
- Outer lipid layer.
- Middle aqueous layer.
- Inner mucin layer.
How does aqueous tear deficiency (aka Keratoconjunctivitis sicca) cause severely dry eyes?
Lacrimal gland dysfunction.
Causes of lacrimal gland dysfunction?
- Inflammation - especially autoimmune.
- Scarring of secretory ducts.
- Excision of lacrimal gland.
How does keratoconjunctivitis sicca differ from Primary Sjogren’s syndrome?
Pure keratoconjuctivitis sicca only involves the lacrimal gland.
Sjogen’s - involves other gland e.g. salivary.
How does secondary Sjogren’s differ from primary?
Secondary occurs in conjunction with a systemic autoimmune disorder e.g. RA.
How does mucin deficiency i.e. xeropthalmia occur?
Large numbers of goblet cells are damaged by extensive conjunctival scarring e.g. alkali burns, cicatrising conjunctival disease), hypovitaminosis A.
Consequences of severe dry eyes?
- Corneal epithelial loss.
- Scarring.
- Vascularisation.
- Corneal thinning (melt) - rare.
- Corneal perforation - rare.
How is dry eye syndrome managed?
- Humidifying environment/ reducing tear evaporation by altering glasses.
- Tear supplements.
- Lacrimal punctal occlusion - temporary (silicone plugs) or permanent (cautery).
How might inappropriate watering of the eye arise?
- Failure of lacrimal drainage system - epiphora.
2. Oversecretion of tears - lacrimation.
Failure of the lacrimal pump to allow drainage is usually due to?
- Facial nerve palsy.
- Ectropion.
Causes of inadequate lacrimal drainage?
- Obstruction.
- Lacrimal pump failure.
Signs of nasolacrimal duct obstruction?
- Mucocele of lacrimal sac.
- Dacrocystits.
Both of which appear at medial canthus.
What is a mucocele of the lacrimal sac?
Non-infected swelling of the lacrimal sac.
What is dacrocystitis?
Lacrimal sac infection.
Causes of watering eyes?
- Blepharitis.
- Dry eyes (paradoxically).
- Entropion, ectropion and ingrowing eyelashes.
- Congenital or acquired nasolacrimal duct obstruction (e.g. dacrocystitis, mucocele).