OnlineMedEd: Pulmonology - "DPLD" Flashcards
What is DPLD?
Diffuse Parenchymal Lung Disease
This is the new name for interstitial lung disease.
Describe the typical presentation of DPLD?
- Chronic, insidious hypoxemic lung disease (years-long development of SOB)
- Dry cough
- Crackles on exam
- Restrictive lung pattern on PFTs
VATS is _______________.
video-assisted thoracoscopic surgery
The definitive diagnosis of DPLD is with _______________.
biopsy of the lungs through VATS
Regardless of the etiology, the mainstay of treatment for DPLD is ______________.
steroids
Give the diagnosis of DPLD based on time.
- Less than 6 weeks: acute interstitial pneumonitis (AIN)
* Greater than 6 weeks: idiopathic pulmonary fibrosis (IPF)
List three rheumatologic conditions that can cause pulmonary fibrosis.
- Systemic lupus erythematosus
- Rheumatoid arthritis
- Systemic sclerosis
Break down the categories of causes of DPLD.
- Drug-induced: bleomycin, amiodarone, radiation, methotrexate
- Rheumatologic: RA, SLE, and SS
- Primary: sarcoidosis
- Environmental: pneumoconiosis (coal, silicosis, berylliosis), hypersensitivity pneumonitis, asbestosis
Cardiac sarcoidosis is diagnosed by _______________.
cardiac MRI (showing inflammation) followed by endocardial biopsy
Why is hypersensitivity pneumonitis an important diagnosis to make?
It is antigen-mediated. The symptoms go away when the person is no longer exposed to the causative factor (barn dust, birds), so treatment is with removal of the agent.