OnlineMedEd: Cardiology - "Cholesterol"

Question 1

The first intervention in cholesterol management should be ________________.

Answer 1

lifestyle modification: diet and exercise

Question 2

What are the four factors that indicate statin use?

Answer 2

• Vascular disease (e.g., unstable angina, known plaques)
• LDL greater than 190
• LDL 70 - 189; older than 40; diabetes
• LDL 70-189; older than 40; calculated risk

Question 3

What things go into the calculated risk?

Answer 3

• HTN
• Smoking
• Obesity
• Age (older than 45 for men or 55 for women)
• Family history

Question 4

List the two high-intensity/moderate=intenstiy statins.

Answer 4

• Rosuvastatin

* Atorvastatin

Question 5

List the two moderate-intensity/low-intensity statins.

Answer 5

• Simvastatin
• Lovastatin
• Pravastatin

Question 6

Everyone who meets one of the four statin indications should start on high-intensity statins. What are the four factors that would make you switch someone to moderate-intensity statins?

Answer 6

• Liver disease
• Renal disease
• Age greater than 75
• Intolerance of high-intensity statins

Question 7

What are the baseline labs you should order prior to initiating statin therapy?

Answer 7

• Lipids
• A1c
• Creatine kinase
• LFTs

Question 8

What should you do if your patient develops statin-induced myositis or hepatitis?

Answer 8

Stop the statin and then reinitiate it once the symptoms resolve.

Question 9

List the two drugs that raise HDL.

Answer 9

• Fibrates
• Niacin

(“Fi and Ni raise the Hi.”)

Question 10

The flushing reaction of niacin can be treated with ______________.

Answer 10

aspirin