One Marks Flashcards
Rabies is identified by
Negri bodies
Neurological complications following rabies vaccines is common with
Semple vaccine
The incubation period of rabies is proportional to
The time taken for virus to travel from the inoculation site to the brain/spinal cord
Rabies reaches the CNS by
Neurotropic spread
Cysticercus cellulose is seen in infection with
T. Solium
Larval of Taenia solium is seen in
Pig
Drug of choice for neurocyticercosis
Albendazole
40 y/o man presented with epileptic seizures. MRI shows multiple ring enhancing lesions with edema in his brain. What is the organism?
Taenia solium
Common cause of keratitis is which virus
HSV 1
Chlamydial trachomatis is most commonly transmitted by
Flies
Rabies characteristics
Enveloped RNA virus
Bullet shaped
Transmitted by bites of infected animals
Vaccine can prevent it
Chronic Otitis Media is usually due to:
a) Aerobic organism only
b) Anaerobic organism only
c) Mixed aerobic and anaerobic organism
d) Staphylococcus aureus
e) Streptococcus pneumonia
Mixed aerobic and anaerobic organism
Chronic Otitis Media
Mixed aerobic and anaerobic organism
All are charecteristics feature of prions diseases EXCEPT:
a) Long incubation period ranging from months to years
b) Predilection for the involvement of the CNS
c) High cell mediated immunity
d) Genetic predisposition
e) Fatal termination
High cell mediated immunity
All are prions diseases of human EXCEPT:
a) Creutzfeldt–Jakob disease (CJD)
b) Fatal familial insomnia
c) Hereditary dementia
d) Kuru
e) Scrapie
Scrapie
Most cases of fungal meningitis are due to:
a) Blastomyces
b) Candida
c) Coccidioides
d) Cryptococcus
e) Histoplasma
Cryptococcus
Trachoma is caused by:
Chlamydia trachomatis serotype A- C
Examination of CSF from a case of meningitis had plenty of lymphocytes and monocytes, reduced glucose and moderate increase in protiens. Which of these organism is most likely the causative organism?
M.TB
The viral encephalitis that can be prevented by vaccine is:
a. Herpes simplex virus type-1
b. Japanese encephalitis virus
c. Rabies virus
d. West Nile encephalitis virus
e. Both ( b & c)
e
Which one of the following statement is CORRECT regarding meningitis and its
diagnosis?
a. In CSF analysis, neutrophil counts are elevated in fungal meningitis
b. Direct intraneural spread along the nerve is the least common route of infection
c. The cause of viral meningitis is diagnosed by India ink stain on a CSF sample
d. Rabies virus is the leading cause of viral meningitis
e. None of the above
b
Neurosurgeon planned to perform cadeveric transplant of dura mater. Which of the following statement is correct regarding the sterilization of instrument used for the surgery in order to prevent transmission of prion diseases?
Instrument sterilized using 0.5% sodium hypochlorite for 2 hour
Which of the following statement is /are TRUE regarding Prions and its diseases?
a. Prions are destroyed by heat and formalin
b. Variant Creutzfeldt–Jakob disease is acquired by corneal transplantation
c. Prions disease can be treated with antiviral medicine
d. Disease of prions have no humoral or cell mediated response
e. All of the above
Disease of prions have no humoral or cell mediated response
A 35-year-old man admitted in the emergency room with complaints of severe
headache, vomiting, seizure and fever (40°C) that began last night. He is “foaming at the mouth” and cannot drink any liquids. He dies after two days. Pathologic examination of the brain reveals eosinophilic inclusion bodies in the cytoplasm of neurons. The most likely diagnosis is:
Rabies encephalitis
Which of the following statements is/are TRUE regarding encephalitis?
a. Japanese B encephalitis is an arthropod borne disease
b. Encephalitis occurs as a complication of measles & poliomyelitis
c. Encephalitis occurs most commonly in adults older than 65 years
d. Borrelia burgdorferi is one of the bacterial agent that cause encephalitis
e. All of the above
e
You have made a clinical diagnosis of meningitis in a 50-year-old immunocompromised woman. A latex agglutination test on the spinal fluid for capsular polysaccharide antigen is positive. Of the following organisms, which one is the MOST likely cause?
Cryptococcus neoformans
. The predominant cell in CSF in case of aseptic meningitis is:
Lymphocytes
Most common agent of neonatal meningitis is:
Streptococcus agalactiae
Which of the following statement is TRUE?
a. Mixed infection with aerobic and anaerobic bacteria is common in CSOM
b. Swimmer’s ear usually caused by Pseudomonas aeruginosa
c. Trachoma causing organism are transmitted by flies
d. Corneal scraping is the ideal specimen for diagnosis of fungal keratitis
e. All of the above
e
Which of the following is the causative agent of East African trypanosomiasis?
Trypanosoma brucei rhodanese
What kind of stain is most commonly used to visualize the capsule of cryptococcus?
negative stain
How do humans usually contract neurocysticercosis?
ingestion of undercooked pork
Which of the following is the most common cause of neonatal meningitis?
Streptococcus agalactiae
How leprosy is primarily transmitted from person to person?
Blowing nose
Which of the following is the causative agent of primary amoebic meningoencephalitis?
Naegleria fowleri
What is the biological vector for African sleeping sickness?
tsetse fly
The symptoms of tetanus are caused by
tetanospasmin
The definitive host for Toxoplasma gondii is
cat
The larval forms of a tapeworm are known as
cysticerci
…. are the most common reservoir for the rabies virus worldwide
Dog
Botulism prevents the release of the …….. neurotransmitter
Acetylcholine
Amplifier host of Japanese B encephalitis is ….
Pig
Which of the following statements is TRUE regarding Influenza virus?
a. It has double-stranded RNA genome
b. Antigenic shift is due to point mutations in HA and NA genes
c. Minor antigenic changes results in pandemics
d. Hemagglutinin & Neuraminidase are surface glycoprotein
e. Preventive vaccines gives lifelong immunity to all stains of influenza virus
d
All are TRUE regarding Histoplasma capsulatum EXCEPT:
a. Transmitted by inhalation of spores
b. Typically dimorphic fungi
c. Resist intracellular killing
d. Causes pneumonia and disseminated infections
e. Infections prevented by vaccine
e
Which of the following bacterial infection is related to formation of
pseudomembrane in oropharynx?
a. Bordetella pertussis
b. Chlamydia pneumoniae
c. Corynebacterium diphtheriae
d. Histoplasma capsulatum
e. Mycoplasma pneumoniae
Corynebacterium diphtheriae
The most common nosocomial respiratory pathogen is:
a. Corynebacterium diphtheriae
b. Haemophilus influenzae
c. Mycoplasma pneumoniae
d. Chlamydia pneumoniae
e. Pseudomonas aeruginosa
Pseudomonas aeruginosa
A 65-year old man presented with complaints of low-grade fever & non-productive cough for the past one week. No organisms could be obtained from routine sputum culture but cold agglutination test was positive. Which one of these pathogens is responsible for the above clinical manifestations?
Mycoplasma pneumoniae
All are true regarding Legionnarie’s disease EXCEPT:
a. Common among heavy smokers
b. Transmitted by water aerosols
c. Clinically presents as atypical pneumonia
d. Infecting organism can be diagnosed by culture on BCYE medium
e. Prevented by subunit vaccine
e
Ghon’s complex in lung is due to:
a. Benign lung tumor
b. Candida infection
c. Influenza infection
d. Mycobacterium tuberculosis infection
e. Streptococcal pharyngitis
Mycobacterium tuberculosis infection
Tuberculosis can be prevented by:
BCG vaccine
Opportunistic fungal pneumonia is caused by:
a. Candida species
b. Aspergillus fumigatus
c. Cryptococcus neoformans
d. Pneumocystis carinii
e. All of the above
e
Middle East Respiratory Syndrome Coronavirus is transmitted by:
a. Close contact with infected person
b. Organ transplantation
c. Exposure to Camels
d. Both (a & c)
e. All the above
d
Community acquired pneumonia is commonly caused by:
Streptococcus pneumoniae
Atypical pneumonia can be caused by:
a. Staphylococcus aureus
b. Chlamydia pneumoniae
c. Streptococcus pneumoniae
d. Haemophilus influenzae
e. None of the above
Chlamydia pneumoniae
All are TRUE regarding Diphtheria EXCEPT:
a. It is localized URT infection with systemic complications
b. Pathogenesis depends on exotoxin production
c. It is severe local inflammation leading to pseudomembrane formation
d. It is caused by Cryptococcus neoformans
e. Can be prevented by effective vaccine
d
A 52-year-old man presented with fever and shortness of breath for 2 days. His
doctor put him mechanical ventilation because of his underlying disease and poor oxygenation. On day 7 of hospitalization, the nurses report purulent endotracheal tube suction specimens. What type of pneumonia does he develop and what is the most common causative agent in this case?
Hospital acquired pneumonia with Pseudomonas aeruginosa
- Which of the following statement is/are TRUE regarding aspiration pneumonia?
a. Caused by polymicrobial organism
b. Common among persons with neuromuscular disease affecting swallowing
c. Due to aspiration of stomach contents into the lungs
d. It results due to inhalation of oropharyngeal secretions
e. All of the above
e
Rash & blisters or ulcers on the hard palate and tongue, seen in hand, foot, and
mouth disease is due to ………………………………………………
Coxsackie A virus
The most common agent of viral pneumonia in adults is:
Influenza virus
Which of the following is included in primary infection with tuberculosis?
a. Progress to develop Ghon Complex
b. Assman focus in apex of lung
c. Cavity in apex of lung
d. Can progress to miliary TB
e. Both a and d are correct
e
Scarlet fever is due to infection by Streptococcus pyogenes producing:
Erythrogenic toxin
The main causative agent of acute otitis media is:
Pneumococci & Hemophilus influenzae
The most important line of treatment of diphtheria is:
Intravenous anti-diphtheritic serum