one health lecture 5- surveillance Flashcards

1
Q

what is monitoring in surveillance?

A

-Routine collection of information on disease
-Often a defined population and time period
-More descriptive and less systematic than surveillance
-Doesn’t necessarily lead to action

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2
Q

what is the difference between eradication and elimination?

A

Eradication - permanent and global, only happened twice
-Smallpox
-Rinderpest

Elimination - restricted to a specific geographic area

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3
Q

when is a disease confirmed as eliminated?

A

-no cases for over 10 years but is this due to lack of detection or true absence?

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4
Q

what are the types of surveillance?

A

-passive
-active = of notifiable diseases and target diseases
-syndromic

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5
Q

what is active surveillance?

A

-health department (or other authority) proactively contacts health care providers or laboratories requesting information about specific diseases

-more costly and labour-intensive

-tends to provide a more complete estimate of disease frequency

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6
Q

what are notifiable disease?

A

-Legal duty to report
-Within 24-72 hours, depending on level of urgency
-Diseases with high public health or economic implications
-Often “exotic” (transboundary diseases)
-On basis of clinical suspicion
-Urgent 0 within 24 hours
-Routine – within 3 days

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7
Q

what is bovine tuberculosis?

A

endemic – already present in the UK, such as bovine TB; Scotland officially free since 2009

Transmission can occur through nose to nose contact and also through contact with saliva, urine, faeces and milk.

exotic – not normally present in the UK, such as foot and mouth disease
Contingency plans…

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8
Q

what is targeted surveillance?

A

-Directed at particular at-risk individuals
Example: cancer screening for those with family history

-Helps improve health outcomes
Early detection ~ more effective treatment options

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9
Q

what is passive surveillance?

A

Regular reporting of observed cases but no active search
-minimum standard, present in most countries
-relatively cheap
-expect underreporting

In contrast to active surveillance (which aims to determine true incidence)

Includes “ad-hoc” reporting (e.g. citizen science)

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10
Q

what are the challenges with wildlife disease surveillance?

A

-Observing and reporting of cases
-Remoteness
-Scavengers
-Topography (landscape) Etc.

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11
Q

what is syndromic surveillance?

A

-Look for rise in the number of people reporting particular types of symptoms, e.g. febrile illness (fever)

-Syndromic surveillance systems monitor data from school absenteeism logs, emergency call systems, hospitals’ over-the-counter drug sale records

-Monitor trends on web or other data collection platforms => “nowcasting”

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12
Q

what is laboratory based surveillance?

A

-Diagnostic confirmation of aetiology (cause) of disease

-More specific than syndromic surveillance

Can detect:
-Pathogen (culture)
-Nucleic acid (PCR)
-Antibodies (ELISA) –> exposure

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13
Q

what are the 2 hypotheses about where our own pathogens come from?

A

1- Co-evolution: pathogens inherited from our ancestors
2- Cross-species transmission: more recent introductions from other species

For most human infectious diseases, genetic data support the second hypothesis

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14
Q

what are the 2 ways to predict zoonotic disease emergence?

A

1- Cataloguing all wildlife pathogens and identify the ones most likely to emerge

2-Better surveillance systems (especially in high-risk regions) to detect emergence as it happens

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15
Q

why do surveillance?

A

1- Gaining basic understanding of epidemiology
2- Early warning system (detect outbreaks)
3- Tracking interventions (assess impact)
4- Inform policy and practice
5- Monitoring variants (e.g. drug resistance)

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16
Q

what is the example of anthrax?

A

~400 cases confirmed in 3 years of active case investigation and sampling vs. < 10 in previous years
BUT
Number of cases greatly affected by completeness of reporting

17
Q

what is the example of wildlife as sentinels of zoonotic disease risk?

A

-Reports of dead crows were useful in defining the geographic and temporal limits of a West Nile virus outbreak in north-eastern US in 1999

-Health department received over 17,000 dead bird reports in 2nd half of year
Suggestion: surveillance system based on bird deaths may provide sensitive method of detecting WN virus

18
Q

what is the problem with syndromic surveillance, with the risk of mis-diagnosis?

A

Malaria uncommon overdiagnosed
Invasive bacterial, mycobacterial, fungal infections high
-bacterial zoonoses common yet unrecognized
-mismatch between clinical diagnoses with actual diagnosis – implications for patient care

19
Q

what does integrating genomics into surveillance allow?

A

Overall, integrating genomics into surveillance enhances the ability to detect, monitor, and control infectious diseases, improving public health outcomes and response times.