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MyNaplex > Oncology-TKI > Flashcards

Oncology-TKI Flashcards

1
Q

Gleevec

A

Imatinib
Used in chronic myelogenous leukemia (CML)
BCR-ABL inhibitors

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2
Q

Sprycel

A

Dasatinib
Used in chronic myelogenous leukemia (CML)
BCR-ABL inhibitors

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3
Q

Tasigna

A

Nilotinib
Used in chronic myelogenous leukemia (CML)
BCR-ABL inhibitors

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4
Q

Iclusig

A

PONAtinib
Used in chronic myelogenous leukemia (CML)
BCR-ABL inhibitors

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5
Q

Bosulif

A

Bosutinib
Used in chronic myelogenous leukemia (CML)
BCR-ABL inhibitors

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6
Q

Zelboraf

A

Vemurafenib
Used in melanoma
BRAF inhibitors

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7
Q

Tafinlar

A

Dabrafenib
Used in melanoma
BRAF inhibitors

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8
Q

Mekinist

A

Trametinib
Used in melanoma
MEK inhibitor used in combination with BRAF inhibitor

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9
Q

Cotellic

A

Cobimetinib
Used in melanoma
MEK inhibitor used in combination with BRAF inhibitor

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10
Q

Gilotrif

A

Afatinib
Used in NSCLC (Non small cell lung cancer)
EGFR inhibitors

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11
Q

Tarceva

A

Erlotinib
Used in NSCLC (Non small cell lung cancer)
EGFR inhibitors

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12
Q

Iressa

A

Gefitinib
Used in NSCLC (Non small cell lung cancer)
EGFR inhibitors

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13
Q

Xalkori

A

Crizotinib

ALK inhibitors

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14
Q

Zykadia

A

Ceritinib

ALK inhibitors

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15
Q

Alecensa

A

Alectinib

ALK inhibitors

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16
Q

Tykerb

A

Lapatinib

HER2 inhibitors

17
Q

Nerlynx

A

Neratinib

HER2 inhibitors

18
Q

Nexavar

A

Sorafenib
Multiple target
Useful in cancers where traditional therapy has little benefits, such as hepatocellular, renal, thyroid cancers

19
Q

Sutent

A

Sunitunib
Multiple target
Useful in cancers where traditional therapy has little benefits, such as hepatocellular, renal, thyroid cancers

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