oncology part 1 Flashcards

1
Q

the cell cycle

A

a sequence of growth stages that a cell moves through for mitosis and regeneration

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2
Q

in order for the cell to undergo mitosis it must go through what stages?

A
G0
G1
S
G2
M
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3
Q

G0

A

cell at rest

not engaged in cycle

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4
Q

G1

A

cells enter cell cycle

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5
Q

S

A

synthesis of structures

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6
Q

G2

A

cells prepare to divide

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7
Q

M

A

mitosis is complete

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8
Q

cancer cells disregard what?

A

the NORMAL cell cycle
they are constantly moving through cell cycle
cells proliferate and accumulate all over each other, may eventually break free to distant body sites

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9
Q

Differentiation

A

the extent that neoplastic cells resemble normal cells both structurally and functionally

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10
Q

anaplasia

A

lack of differentiation, indicates total cellular disorganization, abnormal cell appearance, and cell dysfunction

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11
Q

Grade 1

A

cells are well differentiated

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12
Q

Grade 2

A

cells are moderately differentiated

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13
Q

Grade 3

A

poorly differentiated or anaplastic cells

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14
Q

malignant tumors are graded through

A

I to III

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15
Q

staging classifies the tumors by

A

size, invasiveness, and spread

TNM system

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16
Q

What does TNM stand for?

A

Tumor size, location, involvement
N- lymph node involvement
M- metastasis to distant organs

17
Q

T0

A

no evidence of primary tumor

18
Q

TIS

A

tumor in situ

19
Q

T1-4

A

progressive increase in tumor size or involvement

20
Q

N0

A

no spread to regional lymph nodes

21
Q

N1

A

spread to closest or small number of regional lymph nodes

22
Q

N2

A

spread to most distant or numerous reginal lymph nodes

23
Q

M0

A

no metastisis

24
Q

M1

A

Metastisis

25
Q

Stage 1

A

confined to organ or origin

26
Q

Stage 2

A

locally invasive

27
Q

Stage 3

A

Regional Spread

28
Q

Stage 4

A

spread to distant sites