Oncology Flashcards
1
Q
Tamoxifen mechanism
A
Selective oestrogen receptor modulator - antagonist and partial agonist
2
Q
Indication of tamoxifen
A
Oestrogen receptor positive breast cancer
3
Q
Adverse effects of tamoxifen
A
Menstrual disturbance - PVB or amenorrhoea
Flushes
VTE
*Endometrial cancer - due to agonistic effects
4
Q
Alternative to tamoxifen
A
Raloxifene