General Pharmacology Principles Flashcards

1
Q

Inducers of CYP450

A

Barbiturates
St John’s Wart

Carbamazepine
Rifampicin
Alcohol (chronic)
Phenytoin

Griseofulvin
Phenobarbitone
Sulfonylureas

Smoking

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2
Q

Inhibitors of CYP450

A
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Sodium Valproate
Isoniazid
Cimetidine
Ketoconazole
Fluconazole
Alcohol (acute/binge) + Amiodarone + Allopurinol
Chloramphenicol
Erythromycin
Sulfonamides + SSRIs
Ciprofloxacin
Omeprazole
Metronidazole 

(Grapefruit juice)

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3
Q

Drugs that can cause hyperkalaemia (6)

A
ACE inhibitors/ARBs
NSAIDs
Heparin
Beta-blockers
Spironolactone (aldosterone antagonist)
Cyclosporin/Tacrolimus
Trimethoprim
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4
Q

Name 4 Phototoxic Medications

A

Doxycyline
Amiodarone
Diuretics
NSAIDs

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