General Pharmacology Principles Flashcards
1
Q
Inducers of CYP450
A
Barbiturates
St John’s Wart
Carbamazepine
Rifampicin
Alcohol (chronic)
Phenytoin
Griseofulvin
Phenobarbitone
Sulfonylureas
Smoking
2
Q
Inhibitors of CYP450
A
SICKFACES.COM +1 Sodium Valproate Isoniazid Cimetidine Ketoconazole Fluconazole Alcohol (acute/binge) + Amiodarone + Allopurinol Chloramphenicol Erythromycin Sulfonamides + SSRIs Ciprofloxacin Omeprazole Metronidazole
(Grapefruit juice)
3
Q
Drugs that can cause hyperkalaemia (6)
A
ACE inhibitors/ARBs NSAIDs Heparin Beta-blockers Spironolactone (aldosterone antagonist) Cyclosporin/Tacrolimus Trimethoprim
4
Q
Name 4 Phototoxic Medications
A
Doxycyline
Amiodarone
Diuretics
NSAIDs