Oncology

Question 1

Which screening test lowers mortality the most in breast cancer

Answer 1

Mammography > 50

Question 2

When to use tamoxifen?

Answer 2

• multiple first degree relatives

- estrogen receptor + progesterone receptor +

Question 3

Tamoxifen s/e

Answer 3

Endometrial cancer
DVT
Hot flashes

Question 4

Adjuvant chemotherapy for breast cancer

Answer 4

• > 1 cm
• cancer is in the axilla

More effective if the women is still menstruating

Question 5

Trastuzunab

Answer 5

Monoclonal antibody against Her2/Neu

Good for metastatic disease

Question 6

Breast cancer route

Answer 6

Mammogram—> sentinel lymph node biopsy—> test for estrogen receptor and progesterone receptor —>

Question 7

When to do excisional l.n. Bx in lung cancer

Answer 7

Solitary nodule >1 cm in smokers

Question 8

Lung cancer screening

Answer 8

Chest CT starting at 55 . 55-75 for 30+ year pack of smoking

Question 9

Cervical cancer screening

Answer 9

Start PAP at 21 regardless of sexual activity
Then every 3 years
Then
At 28, do PAP and HPV testing

Give hpv vaccine to all women 13-26

Question 10

Prostate cancer treatment

Answer 10

Localized—>surgery AND external radiation or radioactive pellets

Metastatic —> androgen blockade (flutamide) + (GnRH agonists) leuprolide/ goserelin… but don’t use in cord compression

Question 11

What blood marker in ovarian cancer follows response to therapy and progression of the disease

Answer 11

CA-125

Question 12

Ovarian cancer treatment

Answer 12

Surgical debulking! Even if it’s metastatic

Then
Chemo

Question 13

Testicular cancer

Dx

Tx

Answer 13

Dx:
Inguinal Orchiectomy

Also do… AFP, LDH, and b—Hcg!!!

Ct abd/pelvis for staging
Tx
Localized—> radiation
Widespread —> chemo

Question 14

Prostate cancer follow up

Answer 14

Psa needs to be tested every 6 months for 5 years and thereafter, every year