Allergy and Immunology Flashcards
Angioedema
Hit in the fAce by a pillow or wood chips hitting the arm
Consider placing them in the ICU
Dx C1 esterase inhibitor deficiency g—> low levels of c2 and c4 in the complement pathway—> eccantallide!
Tx FFP and eccantalide, icatibant, androgens like danazol or stanazol for chronic therapy
Angioedema
Tx
Ffp—> acute episodes
Ecantallide and icatibant —> hereditary angioedema
Androgens—> chronic therApy
Allergic rhinitis Tx
Mainstay is to avoid the allergen
Intranasal steroids**. Most important Antihistamines Intranasal antihistamines z( azalAstine) Cromolyn Ipratropium bromide Leukotriene inhibitors Nasal saline spray and wash
Can’t avoid allergens—> desensitation therapy
Favorite step 3 question
Need to stop beta blockers before desensitization
CVID
Recurrent sinopulmonAry I nfectilnss like bronchitis sinusitis pneumonia And pharyngitis
Spruelike abd disorder that presents with malabsorption steatorrhea and diarrhea
Ln adenoids and spleen are present and enlarged
B and T cells are present but the do not make enough Ab so…
Total IvIG is low
Tx infusions of IvIg
X linked agammaglobunemia
Male kid with recurrent sinopulmonAry infectious
Ln adenoids and spleen are diminished in size or absent
B cells are missing as are the immunoglobulins
Tx Same as cvid. Infusions of IvIg
IgA deficiency
Recurrent sinopulmonAry infections
Spruelike abd malabsorption syndromes
Atopic conditions
Anaphylaxis when they receive blood from ppl not like them who are IgA def
Tx; treat the infection as they arise!
IvIg sill not work since there’s no IgA
Hyper IgE syndrome
a rare primary immunodeficiency disease characterized by eczema, recurrent staphylococcal skin abscesses, recurrent lung infections, eosinophilia (a high number of eosinophils in the blood) and high serum levels of IgE.
Recurrent skin infectious caused by staphylococcus
Tx: treat infectious As they come
