Oncology

Question 1

What are the laboratory findings of an intravascular hemolytic anemia?

Answer 1

elevated reticulocyte count, increased LDH level, decreased haptoglobin.

Question 2

Patient with GI complains, poor concentration, anemia and extensor weakness. What is the most likely diagnosis?

Answer 2

Lead poisoning (occupational history). Tx with EDTA or succimer

Question 3

Patient with a PMH of non-small cell lung carcinoma presents after 2 years with a single seizure episode with a solitary cortical mass in the right hemisphere at the gray-white matter junction. What is the most appropriate management for this patient?

Answer 3

surgical resection of the mass

Question 4

Elderly female with multiple ecchymotic areas in the dorsum of her hand. What is the most likely diagnosis? All labs are normal

Answer 4

perivascular connective tissue atrophy

Question 5

Tdt positive with a periodic acid Schiff positive material and a child. With leukocytosis. What is the diagnosis?

Answer 5

Acute Lymphoblastic leukemia

Question 6

recurrent miscarriages with thrombocytopenia and prolonged PTT.

Answer 6

Antiphospholipid antibody syndrome. Usually a positive VDRL. Start them on Low molecular weight heparin

Question 7

Patient with symptoms of leukemia with positive alpha-naphthyl esterase.

Answer 7

Acute monocytic leukemia (FAB M5) leukemia

Question 8

little child with HUS. What is the pathology for RBC loss?

Answer 8

microangiopathic hemolytic anemia