Oncology

Question 1

primary lung tumors have a strong tendency to metastasis in the _______?

Answer 1

the brain

Question 2

Initial S&S of primary lung tumor?

Answer 2

pleural pain and dyspnea (SOB)

Question 3

Most aggressive form of skin cancer?

Answer 3

Malignant melanoma

Question 4

The difference between basel cell carcinoma and squamous cell carcinoma is?

Answer 4

basel cell - bottom layer of epidermis

squamous cell - top layer of epidermis

Question 5

Common place for neurological metastasis?

Answer 5

the brain

Question 6

More common neurological metastasis, primary or secondary?

Answer 6

secondary is 10x more likely

Question 7

What can cause symptoms of neurological metastasis

Answer 7

pressure changes in brain or spinal cord; result in PNS S&S

Question 8

Paraneoplastic syndrome is caused by what 3 things?

Answer 8

• tumor metastasis to brain
• electrolyte imbalance, fluid imbalance, endocrine abnormalities
• remote CNS effects

Question 9

Hepatic malignancy can cause?

Answer 9

bilateral carpal tunnel syndrome

Question 10

Skeletal malignancy can be?

Answer 10

• bone pain
• back pain
• fracture
• hypercalcemia (also effects cardiovascular and GI)

Question 11

Important question to ask pt about their pain..?

Answer 11

does is change when changing positions

Question 12

Is pain a common warning sign of cancer?

Answer 12

pain is rare early warning sign and uncommon in leukemia

• pain is present in 60 - 80% of all solid tumors
• large amount of variation between pt.’s

Question 13

Can treatments change lab values

Answer 13

yes

Question 14

Aerobic exercise is contraindicated when lab values are…?

Answer 14

• platelet count < 10

- WBC count <2,500

Question 15

Common factors of osteosarcoma?

Answer 15

• age 10 - 25

- long bones

Question 16

Common factors of Ewing sarcoma?

Answer 16

• age 5-16
• males > females
• caucasian / hispanic
• in lower extremity

Question 17

Primary bone cancer is found in who?

Answer 17

children and young adults

Question 18

Secondary bone tumors primarily occur in who?

Answer 18

adults with primary cancer in a different system

Question 19

Are sarcoma’s (bone tumor) common?

Answer 19

no, they are relatively rare

Question 20

Common factors of chondrosarcoma?

Answer 20

• older than 40

- pelvis, shoulder, long bones

Question 21

Common factors of osteoid osteoma?

Answer 21

• age 5-16
• males 2-3x greater
• diaphysis (shaft) of bone

Question 22

What is the tumor suppressor gene?

Answer 22

p53