Immunologic Disease Flashcards
Humoral Immunity response is?
takes place in body fluids (extracellular) and is concerned with antibody and compliment activities.
Cell-mediated or cellular immunity is?
primarily intracellular, designed to destroy or contain cells that are recognized by the body as alien and harmful.
When screening any client, what is the most important variable (part)?
the medical history
A recent history of surgery may be indicative of?
bacterial or reactive arthritis, which requires immediate medical evaluation.
Name a red flag to beware of when screening a client with conditions related to immune system dysfunction.
A positive family history for systemic inflammatory or related disorders (may be the only available red flag in this area)
Symptoms of rheumatic disorders often include?
- soft tissue and/or joint pain
- stiffness
- swelling
- weakness
- constitutional symptoms
- Raynaud’s phenomenon
- sleep disturbances
Inflammatory disorders such as RA and polymyalgia rheumatica, are marked (identified) by?
prolonged stiffness in the morning lasting more than 1 hour. stiffness is relieved with activity, but recurs after the person sits down and subsequently attempts to resume activity
Arthropathy in the wrists and proximal small joints of the hands and feet is a typical feature of?
RA
Generalized weakness in the absence of muscle disease is a common symptom of?
Immune system disorder
If weakness is found in one limb without evidence of weakness elsewhere, a ________ disorder may be present.
neurologic
Nail bed changes are indicative of underlying ___________ disease.
inflammatory
Name the 4 Immunological disorders.
- Immunodeficiency disorder
- Hypersensitivity disorder
- Autoimmune disorder
- Immunoproliferative disorder
Immunodeficiency Disorders are defined by?
When the immune system is underactive or hypoactive.
Pain in the knees, hands, wrists, or elbows may indicate and ___________ disorder.
autoimmune
True arthritis produces pain in active ROM, passive ROM or both?
both
Limitations from tendonitis is much worse during _____ ROM.
active
What important clues should we watch out for developing RA, when working with a client who in the first year postpartum.
- increased shoe size
- marked fatigue
- onset of symptoms
Most common site of fracture for the client with RA or ankylosing spondylitis?
lower cervical spine.
When is immediate medical attention needed when working with a client with immunologic disease?
- if exhibiting S&S of anaphylactic shock especially vocal hoarseness, difficult breathing, chest discomfort.
- if a new onset of joint pain with a recent history of surgery.
- if a joint has a dusky blue discoloration or erythema with tenderness, is a sign of a septic or infected joint.
What are the guidelines physician referral when working with clients with immunologic disease?
- new onset of joint pain within 6 weeks of surgery (especially if constitutional symptoms, rash, skin lesions)
- symmetric swelling & pain in peripheral joints (early RA)
- development of progressive neurologic symptoms with in 1 to 3 weeks of previous infection or vaccination.
- evidence of spinal cord compression in anyone with RA, from stiffness to new onset of cervical laxity.
- incontinence in anyone with ankylosing spondylitis.
Signs & Symptoms of RA include? (serious)
How long do S&S of RA need to be present in-order to diagnose?
6 weeks
What protein is responsible for triggering inflammation during a normal immune system response?
cytokines
Therapeutic exercise for persons with RA should be?
- Specific functional training
- Exercises to prevent contractures and improve strength, flexibility, and cardiovascular fitness.
