Oncology Flashcards
0
Q
Examples of tumour suppressor genes
A
p53
pRB
APC
BRCA-1
1
Q
Examples of oncogenes
A
PDGF EGFR ras src myc
2
Q
What is hyperplasia?
A
Increase in cell number
3
Q
What is hypertrophy?
A
Increase in cell size
4
Q
What is atrophy?
A
Decrease in cell size and number in an originally normal organ
5
Q
What is hypoplasia?
A
Reduced size of an organ never reaching full size
6
Q
What is metaplasia?
A
An acquired form of altered differentiation
7
Q
What are the key elements of cancer development?
A
Tumour growth
Angiogenesis
Invasion
Metastasis
8
Q
All neoplasms are monoclonal. What does this mean?
A
Single common ancestor
