Oncology Flashcards
Prevention female
• Monthly self-breast exam over age 20 on days 7-12 of cycle
• yearly clinical breast exam for women >40 years old
Between ages 20-39 needed every 3 years
• annual pelvic exam
• Pap smear: every 3 years if there’s been no problem - no sex, no douche
• Mammogram: yearly starting at age 40 (2 views of each breast) - no lotion, deodorant, powder they show as calcium deposit
• Colonoscopy: at age 50 then every 10 years after that time.
Risk factors
a. Alcohol + tobacco = co-carcinogenic
b. tobacco is the #1 cause of preventable cancer.
c. Suspected dietary causes of cancer:
Low fiber diet, Increased red meat, Increased animal fat, Nitrites (processed sandwich meat), Alcohol, Preservatives, and additives
d. Increased incidence of cancer in the immunosuppressed *That is why there is a higher incidence of cancer > age 60
e. The most important. risk factor for cancer= Aging
f. Diet/exercise habits:
• Cruciferous veggies (broccoli, cauliflower, and cabbage), Vitamin A foods
(colored veggies), and Vitamin C could decrease risk
• Regular physical activity
g. African Americans have a greater incidence than Caucasians.
h. Primary prevention: ways to prevent actual occurrence (sunscreen and no
smoking)
i. Secondary prevention: Using screening to detect cancer early when there is a greater chance for a cure or control
j. Chronic irritation brings about uncontrolled growth of abnormal cells.
Prevention male
- monthly self-breast exam
- Monthly testicular exam- testicular tumors grow fast. Usually 15-36 yrs old
- Yearly digital exam and yearly PSA (prostate specific antigen) for men over age 50
- Colonoscopy at age 50 then every 10 years
General s/s
a. Caution: Change in bowel/bladder habits
A sore that does not heal
Unusual bleeding/discharge
Thickening or lump in breast or elsewhere
Indigestion or difficulty swallowing
Obvious change in wart or mole
Nagging cough or hoarseness
b. Cancer can invade bone marrow→ anemia, hypoxia, and thrombocytopenia
c. Cachexia-extreme wasting and malnutrition
Brachytherapy
Internal radiation
• With all brachytherapy, the radioactive source is inside the client; radiation is being emitted
• Types of Internal Radiation
Unsealed: client and body fluid emit radiation Isotope is given IV or PO
Radioactive for 24-48 hours
Sealed or solid: client emits radiation; body fluids not radioactive Implanted close to or in the tumor
• In general terms, do radiation implants emit radiation to the general environment?
Nursing assignments should be rotated daily, so that the nurse in not continuously exposed.
The nurse should only care for 1 client with radiation implants in a given shift.
• Precautions with Internal Radiation Private room
Wear a film badge at all times
Restrict visitors
Limit each visitor to 30 min per day
No visitors less than 16 years of age
Visitors must stay at least 6 feet from source No pregnant visitors/nurses
Mark the room with instructions for specific isotope
Wear gloves with risk of exposure to body fluids
• How can you help prevent dislodgment of the implant? Keep the client on bedrest.
Decrease fiber in the diet.
Prevent bladder distension.
• What do you do if the implant becomes dislodged and you see it? Gloves, forceps, put in lead container, call radiation to get it.
*Don’t forget this client is immunosuppressed
External radiation
Teletherapy/beam therapy
• Side effects of external radiation are usually limited to the exposed tissues: Erythema
Shedding of skin
Altered taste
Fatigue
Pancytopenia (all blood components are decreased)
• Many signs and symptoms are locatio. And dose related
• Is it okay to wash off the markings? No
• Is it okay to use lotion on the markings? No
• Protect site from sun for 1 year after completion of therapy.
General chemotherapy
Works on the cell cycle
Usually scheduled every 3-4 weeks
Most chemo drugs are given IV via a port.
Many chemo drugs absorb through the skin and mucous membranes; be careful handling them.
Usual side effects: alopecia, N/V, mucositis, immunosuppression, anemia, thrombocytopenia
A vesicant is a type of chemo that if infiltration (extravasation) occurs will cause tissue necrosis.
What are S/S of extravasation? Pain, swelling and no blood return.
The #1 thing to remember with extravasation is prevention! What do you do if this happens?
For NCLEX®, stop the infusion and think vasoconstriction to prevent spreading. Use ice. Call doc. Follow protocol and inject bicarb
Slight increase in temp may mean sepsis
Absolute neutrophil count is most important lab value.
Cervical cancer
a. Risk factors:
• The number one risk factor is Human Papilloma Virus.
• Repeated STD’s
• multiple sexual partners
• Smoking and exposure to second hand smoke
• Dietary factors such as certain nutritional deficiencies: folate, beta-carotene and vitamin C.
• Prolonged hormonal therapy
Mothers who took DES during pregnancy put their daughters at higher risk.
• Family history.
• Immunosuppression
• Sex at a young age and multiple pregnancies
b. S/S:
• Often asymptomatic in pre-invasive cancer
• Invasive cancer symptoms: painless vaginal bleeding
• Other general S/S: watery, blood-tinged vaginal discharge, pelvic pain (and it may occur with intercourse), leg pain along sciatic nerve, and flank/back pain,
• 100% cure if detected early
c. Dx:
• Pap smear. Abnormal? Repeat test
d. Tx: • Electrosurgical excision • Laser • Cryosurgery • radiation and chemo for late stages • Conization- remove part of cervix • Hysterectomy
Uterine/endometrial cancer
a. Risk Factors: • Greater than 50 years of age • Taking estrogen therapy without progesterone • Positive family history • late menopause • No pregnancy (null parity)
b. S/S:
• Major symptoms: post menopausal bleeding
• Other S/S: watery/bloody vaginal discharge, low back/abd pain, pelvic pain
c. Dx: • CA-125 (blood test) to R/O ovarian involvement • Test to evaluate for metastasis: CXR (chest x-ray) CT IVP (Intra Venous Pyelogram) Liver and bone scan BE (Barium Enema) • The most definitive diagnostic test is a D & C (dilatation & curettage) and endometrial biopsy.
1) Surgery: Hysterectomy
• TAH (total abd hysterectomy) = uterus and cervix only! : • Tubes & ovaries removed?
Bilateral oophorectomy (ovaries) Bilateral salpingectomy (tubes)
• Radical Hysterectomy:
2) Radiation: intra-cavitary radiation to prevent vaginal recurrence
3) Chemotherapy: Doxorubicin (Adriamycin®), Cisplatin (Platinol-AQ®)
4) Estrogen inhibitors: Medroxyprogesterone (Depo-Provera®), Tamoxifen (Nolvadex® / Soltamox®)
Radical hysterectomy
• May remove all of the pelvic organs
• Client may have colostomy or ileal conduit
• The greatest time for hemorrhage following this surgery is during the first 24 hours
• Why? Pelvic congestion of blood
• Major complication with abdominal hysterectomy? Hemorrhage
• Major complication with vaginal hysterectomy? Infection
• Will probably have a foley; if she doesn’t you better make sure she does what in the next 8 hours? Voids
• Why is it so important to prevent abdominal distention after this surgery?
We do not want tension on the suture line. Dehiscence and evisceration
• Why do we avoid high-fowler’s position in this client? Because high fowlers will make more blood go where. To the pelvis
• May have an abdominal and perineal dressing to check
• As this client is at risk for pneumonia, thrombophlebitis, and constipation, what is one thing you can do to prevent this? Early ambulation
• Avoid sex and driving. ☺
• Also avoid girdles and douches.
• Any exercise, including lifting heavy objects that will increase pelvic congestion should be avoided.
• Is it possible that the client could hemorrhage 10-14 days after this surgery? Yes
• Is a whitish vaginal discharge okay? Yes, but worry if it changes colors
• Showers OR baths? Showers
Breast cancer risk
- One has a 3 fold risk increase of developing breast cancer if a 1st degree relative (mother, sister, and daughter) had pre-menopausal breast cancer.
- High dose radiation to thorax prior to age 20
- periodonset prior to age 12
- Menopause after age 50
- No pregnancy (null parity)
- First birth greater than 30 years old
Breast cancer s/s
- Change in the appearance of the breast (orange peel appearance, dimpling, retraction, discharge from breast) or lump
- Tail of Spence is where 48% of breast tumors occur: located in upper outer quadrant
Breast cancer treatment
1) Surgery:
• Post op care:
Bleeding→ check dressings, back (pooling of blood), hemovac, Jackson-Pratt drain
Elevate arm on affected side.
Associated nursing care: Stay away from arm on affected side for lifetime of client:
* No watch, no constriction, no BPs or injections, wear gloves when gardening, watch small cuts, no nail biting, no sunburn and no IV
• Brush hair, squeeze tennis balls, wall climbing, flex and extend elbow
• Why? Promotes collateralcirculation
• Look at incision
• Reach to Recovery (Support Group)
• Lymphedema
*Two functions of the lymphatic system:
fights infection and promotes drainage
2) Chemotherapy drugs: Paclitaxel (Taxol®), Doxorubicin (Adriamycin®)
3) Hormonal Therapy:
• Estrogen receptor blocking agents: Tamoxifen (Nolvadex®/
Soltamox®)
• Estrogen synthesis inhibitors: Leuprolide (Lupron®), Goserelin (Zoladex®) (puts them into menopause)
4) Radiation
Lung cancer risk
a. Risk Factors:
• Leading cause of cancer death worldwide
• Five year survival rate is 16%
• Major risk factor: smoking
*When you have stopped smoking for 15 years, the incidence of lung
cancer is almost like that of a non-smoker.
Lung cancer s/s
- Hemoptysis, dyspnea (may be confused with TB, but TB has night sweats), hoarseness, cough, change in endurance, chest pain, pleuritic pain on inspiration, displaced trachea
- May metastasize to bone