Oncology

Question 1

What does FOLFIRI consist of?

Answer 1

5-flourouracil
Leucovorin
Irinotecan

Question 2

Name two topoisomerase 1 ( TOP1 ) inhibitors of Campothecin origin.

Answer 2

1. Topotecan ( for ovarian and lung Ca )

2. Irinotecan ( colorectal Ca )

Question 3

What is the best investigation for lymphoproliferative disorders? ( eg chronic lymphocytic leukaemia ( CLL ) )

Answer 3

Immunophenotyping of the blood

Question 4

When is breast MRI used for patients with invasive breast Ca?

Answer 4

1. If there is a discrepancy regarding the extent of disease from clinical examination, mammography and ultrasound assessment for planning treatment
2. If breast density precludes accurate mammography assessment
3. To assess tumour size if breast conserving surgery is being considered for invasive lobular cancer.