Haematology Flashcards
1
Q
Name the major categories of Von Willebrand disease
A
Type I: partial quantitative deficiency
Type II: qualitative deficiency
Type III: total deficiency
2
Q
Which type of vWD is the most common and what is its manner of inheritance?
A
Type I is the most common.
It is inherited in an autosomal dominant manner, with variable penetrants.
3
Q
Where is the Philadelphia translocation?
A
On 9:22 and it is found in 30-50% of adults who are diagnosed with ALL but it is more classically associated with CML.
4
Q
Name the chromosomes where the alpha and beta hemoglobin genes are located.
A
Alpha is 16
Beta is 11
