Oncology Flashcards
How do prostate cancer bony mets appear on XR?
Sclerotic lesions and pathological fractures
Focal sclerotic bony lesions are indicative of invasive mets
Tumour marker for breast cancer?
Ca 15-3
Tumour marker for pancreatic cancer?
Ca 19-9
Tumour marker for ovarian cancer?
Ca 125
Side effects of anthracyclines?
Cardiomyopathy
Cytotoxic drugs inhibiting DNA + RNA synthesis
e.g. doxorubicin
Bulging forehead veins + blurred vision + positive Pemberton’s sign = ?
SVCO
Bulging veins due to back pressure in venous system
Blurred vision = papilloedema
What is Pemberton’s sign?
Bilateral arm raise → facial flushing
Caused by a goitre compressing the thoracic inlet
What is the BRCA2 mutation associated with in men?
Prostate cancer
What is calcitonin a tumour marker for?
Medullary thyroid cancer
Bones have a ‘medulla’, and are made of ‘calcium’
What is thyroglobulin a tumour marker for?
Follicular or papillary thyroid cancer