Oncology Flashcards

1
Q

How do prostate cancer bony mets appear on XR?

A

Sclerotic lesions and pathological fractures

Focal sclerotic bony lesions are indicative of invasive mets

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2
Q

Tumour marker for breast cancer?

A

Ca 15-3

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3
Q

Tumour marker for pancreatic cancer?

A

Ca 19-9

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4
Q

Tumour marker for ovarian cancer?

A

Ca 125

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5
Q

Side effects of anthracyclines?

A

Cardiomyopathy

Cytotoxic drugs inhibiting DNA + RNA synthesis

e.g. doxorubicin

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6
Q

Bulging forehead veins + blurred vision + positive Pemberton’s sign = ?

A

SVCO

Bulging veins due to back pressure in venous system

Blurred vision = papilloedema

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7
Q

What is Pemberton’s sign?

A

Bilateral arm raise → facial flushing

Caused by a goitre compressing the thoracic inlet

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8
Q

What is the BRCA2 mutation associated with in men?

A

Prostate cancer

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9
Q

What is calcitonin a tumour marker for?

A

Medullary thyroid cancer

Bones have a ‘medulla’, and are made of ‘calcium’

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10
Q

What is thyroglobulin a tumour marker for?

A

Follicular or papillary thyroid cancer

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