Oncological Emergencies Flashcards
What percentage of cancer patients develop metastatic spinal cord compression (MSCC)?
5%
What percentage of cancer diagnoses are based off the first presentation being a MSCC?
20%
Which cancers commonly metastasise to bone and develop MSCC?
Breast
Lung
Prostate
Kidney
What percentage of MSCC occurs in the; Thoracic spine?
60%
What percentage of MSCC occurs in the; Lumbosacral spine?
30%
What percentage of MSCC occurs in the; Cervical spine?
10%
What are the red flag signs for back pain to be aware of?
- Band-like pain around the back
- Pain is poorly responsive to treatment
- Heavy legs or altered sensations in the legs
- Worse on lying flat
- Agonising pain
- Gait disturbance
- Grossly disturbed sleep
- History of Cancer
What would be the immediate management for MSCC?
16mg stat dose of DEX then 8mg Dexamthasone BD
Omeprazole for cover (or any PPI)
What investigation would you arrange for someone presenting with acute MSCC and in what time frame?
MRI whole spine in 24hours of presentation
What would you always consider in a known cancer patient presenting with an acute febrile illness who is receiving chemotherapy?
This MUST be considered to be neutropenic sepsis until proven otherwise!!!
What would be your immediate management of a patient with suspected neutropenic sepsis?
- A-E approach
- Inform senior
- Initiate the SEPSIS 6
What is the Sepsis 6?
- Give O2 (if necessary)
- Cannulate - take blood cultures
- Measure lactate
- Give broad spectrum IV Abx via cannula (e.g. Tazocin and meropenem)
- Give IV fluids
- Measure urine output
What other investigations might you want to perform in a patient presenting with suspected neutropenic sepsis?
- Samples for culture - urine, bloods, sputum (if indicated), CSF (if indicated)
- ABG - lactate and to check for acidosis or alkalosis
- CXR (if indicated)
How quickly should IV Abx be administered to a patient with suspected neutropenic sepsis?
Within 1 hour of presenting
If a known cancer patient presented with the following, what is your main diagnosis and what would your management be; Neck and face swelling. headache, blurred vision?
Superior vena cava obstruction (SVCO)
- A-E assessment
- Steroids
- Stent
- Chemotherapy or radiotherapy