ONCOLOGIA PEDIATRICA Flashcards

1
Q

Cual es el cancer mas comun en niños?

A

LEUCEMIA (70%)
79% Leucemia linfoblastica aguda
17% Lecuemia mieloide aguda

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2
Q

Dos tumores mas comunes del SNC?

A

Astrocitoma

Meduloblastoma cerebelosos

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3
Q

Tumor neurologico extracraneal mas comun?

A

NEUROBLASTOMA

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4
Q

Tumores oseos mas comunes?

A

Osteosarcoma y el Sarcoma de Erwing

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5
Q

Tumor renal mas comun?

A

Tumor de Willis

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6
Q

Tumor abdominal mas frecuente?

A

Neuroblastoma

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7
Q

Origen del neuroblastoma?

A

Alteracion de las celulas de la cresta neural

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8
Q

Rango de edad de dx del neuroblastoma?

A

< 5 años (90%) especialmente en < 2 años

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9
Q

Dos lugares mas comunes de aparicion del neuroblastoma?

A

Abdominal (70%) y Mediastino Posterio (20%)

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10
Q

Que es el sx de kinsbourne asociado al neuroblastoma?

A

ataxia, mioclonia y movimientos involuntarios

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11
Q

Que tipo de diarrea y porque se produce en el neuroblastoma?

A

Diarrea secretora por sobreproduccion del peptido intestinal vasoactivo

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12
Q

HTA-Taquicardia - Sudoracion x catecolaminas se asocia con que tipo de tumor?

A

Feocromocitoma

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13
Q

Dos vias de metastasis del neuroblastoma

A

Linfatica y Hematogena

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14
Q

4 organos mas comunes de metastasis del neuroblastoma

A

Medula osea
Hueso
Higado
Piel

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15
Q

La infilitracion severa hepatica por el neuroblastoma se conoce como?

A

Sx de Pepper

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16
Q

Marcador asociado con neuroblastoma?

A

Catecolaminas elevadas en orina

17
Q

En oncogen N-myc es de pronostico en el neuroblastoma?

A

MALO

18
Q

El oncogen TRKA es de pronostico en el neuroblastoma?

A

BUENO

19
Q

Estadio I-II o I-II-IV en < 1 año en neuroblastoma el TTO es?

A

CX

20
Q

Estadio III de neuroblastoma el tto es?

A

QUIMIO + CX

21
Q

Estadio IV o mal pronostico del neuroblastoma el tto es?

A

CX - QUIMIO - Inmunoterapia - Trasplante de medula osea

22
Q

segundo tomar abdominal mas frecuente?

A

Tumor de Wills (nefroblastoma)

23
Q

Con que cromosoma y gen esta asociado?

A

Chr 11 gen WT1

24
Q

Malformaciones asociadas mas comunes?

A

Aniridia
Hemihipertrofia
Malformacion genitourinarias

25
Q

Sx de Beckwith-widerman es?

A

Macroglosia
Hemihipertrofia
Viscero megalias
Onfalocele

26
Q

Que sx es el mas comun asociado al tumor de wills?

A

Sx de Beckwith-widerman es?

27
Q

Metastasis mas comunes del Tumor de Wills?

A

Ganglios linfaticos
PULMON
higado