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USMLE Step 1 > Oncogenes > Flashcards

Oncogenes Flashcards

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USMLE® Step 1 flashcards
1
Q

abl

A

tyrosine kinase - CML

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2
Q

c-myc

A

transcription factor - Burkitt’s Lymphoma

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3
Q

bcl-2

A

anti-apoptotic - follicular, undifferentiated lymphoma

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4
Q

HER2/neu (c-erbB2)

A

tyrosine kinase - Breast, ovarian, gastric carcinomas

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5
Q

ras

A

GTPase - colon carcinoma

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6
Q

L-myc

A

transcription factor - lung tumor

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7
Q

N-myc

A

transcription factor - neuroblastoma

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8
Q

ret

A

tyrosine kinase - MEN 2A, 2B

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9
Q

c-kit

A

cytokine receptor - gastrointestinal stromal tumor (GIST)

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USMLE Step 1 (8 decks)

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