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Step1 > Oncogenes > Flashcards

Oncogenes Flashcards

1
Q

Bcr-able

A

Tyrosine kinase.

CML, ALL

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2
Q

Bcl-1

A

anti-apoptotic molecule.

Follicular and undifferentiated lymphomas.

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3
Q

BRAF

A

Serine/threonine kinase.

Melanoma

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4
Q

C-kit

A 
Cytokine receptor (for stem cell factor).
Gastrointestinal stromal tumor (GIST)
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5
Q

C-myc

A

Transcription factor.

Burkitt lymphoma

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6
Q

HER2/neu (c-erbB2)

A

Tyrosine kinase.

Breast, ovarian, gastric carcinomas.

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7
Q

L-myc

A

Transcription factor

Lung tumor

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8
Q

N-myc

A

transcription factor.

Neuroblastoma.

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9
Q

Ras

A

GTPase.

Colon cancer, lung cancer, pancreatic cancer.

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10
Q

Ret

A

Tyrosine kinase.

MEN 2A and 2B.

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Step1 (14 decks)

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