old white men Flashcards
development of the microscope and named “cell” by looking at corks
Robert Hooke
prove that spontaneous generation of cells/organisms does not now occur on Earth
Louis Pasteur
meat experiment
shows limitation of cell theory: where did the first cell emerge from?
Francesco Redi
protein lipid sandwich
how did they discover it?
Davson and Danielli
due to evidence from electron microscopy
phospholipid unstained while proteins stained
fluid mosaic model
what did it falsify?
how did they discover it?
Seymour J. Singer + Garth L. Nicolson
falsified the Davson-Danielli model
freeze-fracture electron micrograph: globular proteins present in the center of the phospholipid bilayer
model making to discover the structure of DNA
Francis Crick and James Watson
evidence for the semi-conservative replication of DNA
spun samples of DNA with 15N in 14N medium
Meselson and Stahl
made θ diagram of DNA being unzipped
Cairns
experimental results on how pea plants passed on their characteristics
pure-bred short x TALL plants: castrate the plant to prevent self-pollination
Gregor Mendel
develop evolution by natural selection
Darwin and Wallace
environmental changes created needs that caused organisms to modify their existing structures to meet these needs
acquired characters would be passed on to later generations
Lamarckism
did an experiment to falsify Lamarck’s idea
cut rat tails
August Weismann
he was not the first to use the idea of genus, but he popularised its use along with the species name in a consistent way
Genus species
Carolus (Carl) Linnaeus
falsified theories developed by the ancient Greek philosopher Galen
discovery of the circulation of the blood with the heart acting as the pump
hampered in his observational research into reproduction by the lack of equipment
William Harvey
discovered penicillin
was examining culture plates on which he had grown Staphylococcus bacteria
one plate had a green mould Penicillium notatum growing with no bacteria
Alexander Fleming
develop a method of producing the penicillin in liquid cultures and purifying the penicillin in these cultures
Howard Florey and Ernst Chain
initially it was unclear whether genes were made of protein or DNA
2 strains of such T2 were used, one DNA had radioactive 32P and the other had radioactive 35S protein coat
the radioactive element 32P was in the bacteria
Alfred Hershey and Martha Chase
developed high resolution detectors that produce clear diffraction patterns in DNA
provided crucial evidence that DNA is a double helix
Rosalind Franklin and Maurice Wilkins
discovered the Calvin cycle and the carboxylation of RuBP
used the green alga Chlorella and radioactively labelled carbon dioxide (14CO2) and hydrogen carbonate (HCO3-) to follow the path of carbon in photosynthesis
lollipop algae shit
Melvin Calvin (and Andrew Benson)
chemiosmosis theory: completely new and proposed an indirect interaction between these enzymes with no intermediate compound
Peter Mitchell
discovered non-Mendelian ratios in drosophila
developed his ideas of gene linkage to explain the results
Thomas Hunt Morgan
equation: p^2 + 2pq + q^2 = 1 p = frequency of dominant allele q = frequency of recessive allele p + q = 1 frequency of genotypes TT = p^2 Tt = 2pq tt = q^2
Hardy-Weinberg
administered the very first vaccine
noticed that people who milked cows that have cowpox almost never contracted the very serious disease smallpox
Edward Jenner