Ointments and Creams Flashcards

1
Q

Ointment definition

A

Semisolid preparation that is intended for the skin or other mucous membranes.

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2
Q

Are all ointments medicated?

A

no

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3
Q

What can unmedicated ointments be used for?

A

Physical Effects as protectants, emollients or lubricants

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4
Q

What can an ointment base be used for?

A

Can be used as vehicles for medicated ointments or for their physical effects

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5
Q

Four types of ointment bases?

A

Oleaginous
Absorption
Water-removable
Water-soluble

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6
Q

Define Oleaginous Bases

A

Hydrocarbon bases
Can have an emollient effect and protect against the escape of moisture. Can be effective for a long period of time.

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7
Q

T/F: Oleaginous bases contain water, and when theyre added, they are added with ease.

A

FALSE. Do not contain much water & if they are, it’s HARD to add them. SMALL AMOUNTS

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8
Q

Name four oleaginous bases

A

Petrolatum, USP
White Petrolatum USP
Yellow Ointment , USP
White Ointment, USP

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9
Q

Petrolatum, USP commercially

A

Vaseline

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10
Q

Petrolatum, USP- color

A

yellow- amber color

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11
Q

Can Petrolatum can be used alone or in combination with other agents?

A

Yes, to both.

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12
Q

White petrolatum, USP

A

Decolorized version of petrolatum

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13
Q

Benefits of having white petrolatum be decolorized?

A

More esthetically pleasing to patients and to pharmacists

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14
Q

Commercial product of White petrolatum?

A

White Vasline

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15
Q

Yellow Ointment USP. How is it formulated?

A

Yellow Wax and petroleum mixed together

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16
Q

What is yellow wax?

A

Obtained from honey combs of bees

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17
Q

How is Yellow Ointment created?

A

Melting yellow wax in a water bath and adding the petrolatum until the mixture is uniform and then cooling it down.

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18
Q

White Ointment, USP

A

White Wax and white petroleum mixed together

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19
Q

What is white wax?

A

Bleached and purified yellow wax

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20
Q

Name the two types of absorption bases

A

Those that permit aqueous solutions (W/O) emulsions, and those that ARE W/O emulsions and allow for more aqueous solutions.

21
Q

Are absorption bases easily removed from the skin? why or why not

A

NO. The external phase of absorption phases is oil. So it will not wash easily

22
Q

Why are absorption bases useful (in terms of aqueous solutions) ?

A

Because they are used to incorporate small amounts of aqueous solutions into hydrocarbon bases.

23
Q

How can absorption bases be used to incorporate water into hydrocarbon bases?

A

Incorporating the aqueous solution into the absorption base which is then added to the hydrocarbon base

24
Q

Hydrophilic Petrolatum formulation

A

Cholesterol
Stearyl Alcohol
White Wax
White Petrolatum

25
Q

How can Hydrophilic Petrolatum be made? Steps

A

Melting stearyl alcohol in a steam bath, adding cholesterol and dissolving, adding white petrolatum and mixing and then stirring until congealed

26
Q

Commercial version of hydrophilic petrolatum?

A

Aquaphor.

27
Q

What is useful about adding drugs to an absorption base like Aquaphor

A

Have the capacity to hold three times its weight in water. Can be useful to incorporate medication into this base.

28
Q

What % of Eucerin is a W/O Emulsion?

A

50%

29
Q

How is Lanolin, USP made?

A

Obtained from the wool of sheep and cleaned and purified.

30
Q

What type of base is lanolin?

A

Absorption Base

31
Q

What type of base is Hydrophilic Petrolatum?

A

Absorption Base

32
Q

Modified Lanolin, USP

A

Absorption base

33
Q

How is Modified Lanolin, USP created?

A

Is lanolin that ice processed further to reduce the contents of free lanolin alcohols and detergent residues

34
Q

Water removable bases

A

Oil in water emulsion resembling creams. O/W

35
Q

What is the external phase of a water removable base?

A

Aqueous.

36
Q

Is it easy for a water removable base cream, to be removed from the skin?

A

Yes, it has an external phase that is aqueous.

37
Q

Hydrophilic Ointment, USP

A

Water removable base

38
Q

T/F: Water removable bases can absorb serous discharges

A

True

39
Q

If a wound is leaking water, what type of ointment would you put on it?

A

Any water -removable base ointment like Hydrophilic Ointment, USP

40
Q

Role of Sodium Lauryl Sulfate in a formulation

A

Emulsifying agent

41
Q

Formulation contains stearyl alcohol and white petrolatum. What phase is this considered?

A

This is the oleaginous phase of the emulsion

42
Q

If there are other ingredients like purified water, what phase would this be considered?

A

The aqueous phase

43
Q

What is the role of ingredients like methylparaben & Propylparaben?

A

preservatives

44
Q

T/F: Water-soluble bases contain many oleaginous components

A

FALSE. NONE

45
Q

are water-soluble bases easily water washable?

A

Yes, they are even referred to as greaseless.

46
Q

Should we add alot of water to a water soluble base

A

NOOOOOOOOOO
It is used for the incorporation of solid substances

47
Q

PEG Ointment

A

Example of a water-soluble base

48
Q

PEG physical properties

A

Clear, colorless liquids and pliable semisolid liquid.