oddities Flashcards
What are the filling pressures like in heart failure
Normal or high
What symptoms does left heart failure lead to
Lung symptoms: pulmonary oedema, orthopnoea, paroxysmal nocturnal dysponea, fatigue
What symptoms does right heart failure lead to
Body symptoms: pedal oedema, raised JVP, ascites, hepatomegaly
Definitive treatment of heart failure
TAVI
Acute management of heart failure
High flow oxygen, IV GTN, IV furosemide, IV morphine
Who gets pneumococcal and influenza vaccines
COPD and HF
2nd line treatment for heart failure
Spironolactone
3rd line treatment for heart failure
Candesartan and hydralazine
Causes of dilated cardiomyopathy
Alcoholic or idiopathic
Treatment of hypertrophic cardiomyopathy
Amiodarone
Symptoms of cardiomyopathy
Dyspnoea, fatigue, pulmonary oedema and emboli
First line treatment of pericarditis
Cardiocentesis
Second line treatment of pericarditis
Ibuprofen, Omeprazole, Colchicine, Exercise restriction
Triad of signs of pericarditis
Low BP, Raised JVP, Muffled HS
Treatment of aortic aneurysm
Asprin, Ace Inhibitor, Beta blocker, Statin
Treatment of aortic dissection
ABCDE, labetalol and morphine before surgery
Treatment post aortic repair
HTN below 120, BB and ACEI
Lead V1-V4 artery and area
LAD, Anterior/ Septal
Leads 2,3,AVF artery and area
RCA, inferior
Leads V5,6 and 1, artery and area
Circumflex and lateral
Stage 2 hypertension values
160/100 or 150/95 at home
Angina ongoing treatment
GTN, Aspirin, BB, Statin
Advice about taking GTN
Expect pounding headache and light head
Take, 5 mins, take, 5 mins, take phone ambulance
Signs of VSD and AVSD
Systolic murmur and thrill
Cardinal sign of coarctation
Right arm hypertension
Cyanotic structural heart disease without shunts
Coarctation, congenital AS
Acyanotic structural heart disease without shunts
Pulmonary stenosis, tricuspid regurg
Treatment of structural heart disease
Surgery, IE prophylaxis
Regular broad complex tachycardia
VT
Give amiodarone
Regular narrow complex tachycardia
SVT
Vagal Manouveres
Adenosine
Wolf parkinson white ECG
Delta waves (slope on the Q)
Sustained ventricular tachycardia
VT/ ectopic lasting more than 30s
Non sustained ventricular tachycardia
VT/ ectopic lasting less than 30s
Digoxin antidote
Digoxin Immune Fab
AV node reentrant tachycardia
Often young people, most common SVT
Describe sarcoid features
Non caseating granulomas
Bilateral lymphadenopathy, fibrosis, fever,arthralgia
Young black woman
Diagnosis of sarcoid
Bronchoscopy and biopsy
Features of IPF
Clubbing, fibrosis
Diagnosis of IPF
High resolution chest CT
Treatment of IPF
IV prednisolone
Antifibrinolytic for IPF
Perfenidone
Active TB 1st investigation
CXR
Active TB diagnostic investigation
Sputum for NAAT
What do you give to treat isoniazid neuropathy
Pyridoxine
How long do you treat CNS TB for
12 months
Potts Disease
Spinal TB
Pulmonary Hypertension clinical findings
Loud Second Pulmonary HS
Treatment of H Influenza pneumonia
Amoxicillin
Treatment of S Aureus pneumonia
Flucloxacillin
Treatment of pulmonary hypertension
Diuretics, Calcium Channel Blockers, ?LTOT
Treatment of pseudomonas
Ciprofloxacin
Diagnosis of bronchiectasis
High resolution CT Chest
Treatment of bronchiectasis
Firstly: Exercise and Diet. Then chest Physio, nebulised saline and salbutamol
Exudative pleural effusion
High protein, Infection, Cancer, PE, Connective tissue disorders
Transudative pleural effusion
Low protein, cardiac, renal, liver failure, Meigs, hypoalbuminaemia, hypothyroid
Treatment of pleural effusion
Thoracocentesis then furosemide
Treatment of a secondary pneumothorax less than 1cm in size
Oxygen and observe
Treatment of a secondary pneumothorax in a patient over 50
Chest drain
Wegeners features
Nasal, lung and glomerulonephritis
Other name of wegeners
Granulomatosis with Polyangitis
Treatment of GPA/ Wegeners
IV prednisolone
Methotrexate
Folic acid
How do you diagnose goodpastures
Renal biopsy= cresenteric glomerulonephritis
Treatment of goodpastures
1- IV pred
Definitive- plasmaphoresis
Where can mesothelioma involve
Pleura, perineum, pericardium and testes
Describe pleuritic fluid in mesothelioma
Bloody and straw coloured
PE Wells score over 4
Skip D Dimer, go straight to CTPA
How long on a DOAC for a provoked PE (not cancer)
3 months
When and how do you use fibrinolysis in PE
Alteplase when they are haemodynamically unstable
How do you treat a meconium ileus
Constrast enema and lactulose
What is a gene modulator for CF
Ivacafter
What does the FBC of a COPD patient show
Secondary polycythaemia
How do you treat an infective exacerbation of COPD
Amoxicillin and Prednisolone
What virus can cause a COPD exacerbation
Rhinovirus
Which virus commonly causes tonsilitis
Adenovirus
Name 2 nasal decongestants used for sinusitis
Pseudoephidrine, oxymetalozine
Treatment of croup
Adrenaline nebulised, dexamethasone, oxygen, fluids
Treatment of epiglottitis
Intubation and IV fluids
Score used for common cold
CENTOR/McIsaac
What is needed for diagnosis of pneumonia
Chest XR
Pneumonia treatment in penicillin allergic patient
Cefuroxime
Post influenzae pneumonia cause
staph aureus
Gram negative hospital acquired pneumonia
E Coli
ITP, Encephalopathy, Pneumonia, Diagnose on serology
Mycoplasma Pneumonia
Hypernatraemia and Pneumonia
Legionella, diagnose with urinary antigen
Treatment of atypical pneumonia
Erythromycin
Features of adenocarcinoma
Non smokers, gynaecomastia, HPOA
What warrants a 2WW for lung cancer
40 + and haemoptysis
CXR suspicious of cancer
40 + and 2 symptoms suspicious of cancer
Asthma questions to ask in hisotry
Last 3 months
- nocturnal waking
- daily symptoms
- affecting ADLs
COPD questions to ask in history
Home Oxygen?
How Many Exacerbations?
How Many Rescue Packs?
How Many Admissions?
Diagnostic for cholecystitis when query sepsis
CT
What are 2 things that bile stones can be made of
90% cholesterol, 10% calcium bilirubinate
What type of cancer is oesophagea
Adenocarcinoma
Where does oesophageal cancer metastasise to
Lung and liver
Describe two distinct features of gastric cancer
Epigastric pain that doesn't radiate Tingling feet (from b12 deficiency)
Treatment of gastric cancer
Chemo and surgical resection
What type of cancer is pancreatic cancer
Ductal adenoma
Investigation for pancreatic cancer
CT and tumour markers
Where is the pain for pancreatic cancer
Epigastric/ RUQ/ LUQ but radiates to the back
What type of cancer is colorectal cancer
Adenocarcinoma
Bowel cancer screening
FIT/FOB testing for 60-74 year olds, once every 2 years
Diagnostic investigation for colorectal cancer
Colonoscopy
What imaging is used for staging colon cancer
CT
What imaging is used for staging rectal cancer
MRI
Treatment fo severe colon cancer
Radiotherapy
Treatment of mild rectal cancer
Transanal excision
First line treatment of an acute crohns flare
IV hydrocortisone
Second line treatment of acute crohns flare
Azathioprine
Third line treatment of acute crohns fare
Infliximab
Complications of crohns
Fistulae, abscesses, colon cancer
Extra GI features of crohns
Arthropathy, erythema nodosum, pyoderma gangrenosm. Uveitis and episcleritis
Treatment of a symptomatic hernia
Laparoscopic mesh repair
Chronic diarrhoea and malabsoprtion diagnosis and management
Giardiasis and metronidazole
What causes Guillain Barre Syndrome
Campylobacter
Whats the likely causative organism when the diarrhoea is bloody with abdominal pain
Shigella
Vomitting and diarrhoea within 6 hours of ingesting dodgy food
S Aureus
Which two bloods can rule out appendicitis
FBC and CRP
How do you treat appendicitis if theyre not for surgery
Antibiotics
Distinctive blood result of diverticulitis
Polymorphonuclear lymphocytosis
Treatment of diverticulitis
Increase fibre in diet, analgesia and antibiotics
Where is the pain in pancreatitis
LUQ
Invesigation for acute pancreatitis
Serum lipase
Investigation for chronic pancreatitis
Abdominal ultrasound
Symptoms of hereditary haemochromatosis
Bronze skin, hepatomegaly, diabetes, likely post menopausal if female
Diagnostic investigation for hereditary haemochromatosis
HFE gene testing
Treatment of hereditary haemochromatosis
Desferrioxamine
Diagnostic investigation for wilsons disease
24 hour urinary copper excretion
Treatment of wilsons disease
Zinc
Alpha 1 antitrypsin deficiency first linvestigation
Spirometry and LFTs
Alpa 1 antitrpysin deficiency diagnostic investigation
Plasma alpha 1 antitrpysin level
First treatment in Alpha 1 antitrpysin deficiency
Smoking cessation
Investigation for ascites
Ultrasound
Investigation for spontaneous bacterial peritonitis
Ascitic fluid- absolute neutrophil count
Symptoms of volvolus
Abdo pain and bilious vomiting
Investigation for volvolus
Upper GI contrast CT
Treatment of volvolus
Ladd procedure
Hep A first line investigation
Anti HAV antibody
Hep A diagnostic investigation
HAV RNA
First line treatment of Hep B
Interferon alpha
Long term treatment of Hep B
Tenofovir
Hep C first line investigation
Anti HCV antibody
Hep C diagnostic investigation
HCV RNA
Hep D first line investigation
Anti HDV antibody
Which of the Hepatitises are RNA
ACE
Hep E first line investigation
Anti HEV antibody
Hep E diagnostic investigation
HEV RNA
What should be calculated for alcoholic cirrhosis
Discriminant function (bilirubin and PTT)
Treatment of ascites
Spironolactone
Treatment of portal hypertension
Propanolol
Treatment to prevent hepatic encephalopathy
Lactulose
What causes UC flares
NSAIDs and stress
UC on biopsy
No granulomas or inflammation beyond submucosa, reduced goblet cells, crypt abscesses
What is mild UC flare
Less than 4 stools a day
Second line treatment of Acute Severe UC flare
IV Ciclosporin
Third line treatment of Acute Severe UC flare
Infliximab trial
PBC and PSC treatment
Ursodeoxycholic acid
PSC diagnosis
ERCP
New painless obstructive jaundice
Pancreatic cancer
Well person, new jaundice after new drug/ antibiotic
Acute drug induced liver injury
Bloods for coeliac
IgA TTG and serum IgA levels
Associated symptoms of coeliac
Dermatitis Herpetiformis Osteomalacia Enteropathy associated T cell lymphoma of small bowel Hyposplenism Anaemia
What does dermatitis herpetiformis look like
Cluster of itchy bumps, eczema like
Anaemia of B12, Folate and IDA after travel
Tropical sprue
Investigation for haemorrhoids
Anoscopic examination
First line treatment for haemorrhoids
Diet and lifestyle change
Second line treatment for haemorrhoids
Topical hydrocortisone
Third line treatment for haemorrhoids
Band ligation
Investigation for anal fistulae
MRI and ultrasound
Treatment of anal fistulae
Fistulotomy and drainage
Anal fissure symptoms
Tearing sensation, blood, defecation pain
Anal fissure treatment
Lifestyle, topical GTN
GORD treatment
8 week PPI and lifestyle measures
What do you give if nocturnal symptoms with GORD
Rantidine
When do you do an OGD in GORD
Over 55 Weight Loss More than 4 weeks OR Relapsing
What treatment does mallory weiss tear need
Resolves spontaneously
Diagnosis of mallory weiss tear
OGD
Plummer vinson syndrome
Glossitis, IDA and dysphagia
Boerhaave syndrome
Retrosternal chest pain, vomiting, surgical emphysema
Eradication of H Pylori
Amoxicillin (or metronidazole) + clarithromycin + omeprazole for 7 days
Treatment of varices
Blood, terlipressin, prophylactic ceftriaxone
Investigation of varices
OGD, NILS
Symptoms of scleroderma
CREST and fibrosis and renal
limited systemic sclerosis antibody
Anti centromere antibody
Diffuse systemic sclerosis antibody
Anti Scl 70/ antitopoisomerase
First line treatment of IBS
Lifestyle and FODMAP
2nd line treatment of IBS
Constipation: lactulose
Diarrhoea: loperamide
Requirements for IBS diagnosis
1 day a week for past 3 months with 2 of
- altered stool frequency
- altered stool form
- pain associated with defecation
Treatment for unstable patient with SBO Sx or AXR suggestive of SBO
CAT 1 laparatomy
Investigation for stable patient with SBO Sx or AXR suggestive fo SBO
CT with contrast
Features for surgery in small bowel obstruction
Bowel ischaemia
Closed loop obstruction
Obstructive lesion
Tympanic abdomen
Large bowel obstruction
Investigation for large bowel obstruction
AXR
Charcot Marie Tooth
Motor inherited neuropathy. Frequently sprained ankles. Foot abnormalities
Posterior spinal cord neuropathy
Romberg positive, sensory
Lateral spinal cord neuropahty
UMN signs (motor) and spastic
Describe alcohol neuropathy and treatment
Sensory then motor. Treatment is pabrinex
Important thing to do after giving prednisolone in GCA
Opthalmology review
Severe stabbing pain in one side of face
Trigeminal neuralgia
Treatment of parkinsons
Levodopa (dopaminergic) and Carbidopa (decarboxylase inhibitor)
Incontinence, dementia and ataxia
Symptoms of normal pressure hydrocephalus
Investigation for normal pressure hydrocephalus
MRI and CSF flow studies
Treatment of normal pressure hydrocephalus
Ventriculoperitoneal shunt
Diagnosis of huntingtons
CAG repeat testing (more than 40)
Treatment of huntingtons
Symptomatic- SSRI or haloperidol
DMARD in MS
Interferon beta
Acute treatment in MS
Methylprednisolone
Symptoms of MS
Foot drop, UMN, optic neuritis, Lhermittes electric shock down spine
Investigations for Myasthenia Gravis
Serum anticholinesterase receptor antibodies
Muscle Specific Tyrosine kinase antibodies
What imaging might you do in Myasthenia Gravis
CT chest looking for thymoma
Treatment for MND
Riluzole and supportive care
Investigations for meningitis
LP, blood cultures, bloods inc lactate
Who gets amoxicillin added on for meningitis
Over 50 or under 3 months
What do you treat meninigitis with
Cefuroxime (+amox) and IV dexamethasone
Treatment of fungal meningitis
Amphotericin B
Treatment of viral meningitis
Aciclovir (as likely HSV)
Treatment of CMV
Ganciclovir
Investigation of encephalitis
MRI
How long does a TIA last
Up to 24 hours
Investigation of TIA
ECG and bloods (FBC, clotting, U and E, glucose)
Whats the treatment of TIA
300mg aspirin
Long term clopidogrel and statin
16-30 year old with spinal cord compression
Trauma
30-50 year old with spinal cord compression
Disc disease
40 plus year old with spinal cord disease
Malignancy
Acute onset spinal symptoms
Trauma or disc herniation
Chronic onset spinal symptoms
Osteoporosis, osteomyelitis or malignancy
Treatment of spinal cord compression
Immobilisation and decompressive laminectomy
Treatment of spinal malignancy
Corticosteroids, surgery and radiotherapy
What tissue do most pancreatic cancers come from
Exocrine
Imaging for abscess
Ultrasound
Hayfever treatment
Daily oral antihistamine, daily nasal steroid
Who gets an erythematous rash with amoxicillin
Allergic, CLL and infectious mononucleosis
Most common brain tumour
Astrocytoma
Investigation for astrocytoma
MRI and surgical biopsy
Progression of astrocytoma
Pilocytic, diffuse, anaplastic, glioblastoma multiforme
Visible bony growth, brain tumour
Meningioma
Child, vomiting relieves headache
Medulloblastoma
Medulloblastoma imaging
CT and MRI
Treatment of medulloblastoma
Resection
Mild head injury GCS
13-15
Moderate head injury GCS
9-12
Severe head injury GCS
<9
Vision change caused by parietal lobe problem
Inferior vision
Vision change caused by temporal lobe problem
Superior vision
Vision change caused by pitiutary tumour
superior quadrant defect
Vision change caused by craniopharyngoma
Inferior quadrant defect
Treatment of brain bleeds
Phenytoin
Removal of anticoagulation
Treatment of subarrachnoid haemorrhage
ABCDE and nimodipine
2nd line epilepsy medication
Lamotrigine
How long does an epileptic need to be seizure free before they can drive
1 year
How long do you have to be seizure free after 1 seizure if not epileptic
6 months
3 things for Total anterior circulation stroke
Honomymous hemianopia, motor, cognition
1st line treatment of stroke
Alteplase within 4.5 hours
Contraindication for alteplase for stroke
Bleeding anywhere or neuro disease
Alternative to alteplase for stroke
Thrombectomy in 6 hours
Long term medications after stroke
Clopidogrel and statin
AF and stroke, anticoagulant choice
DOAC not clopidogrel
Imaging for stroke
Carotid artery doppler and CT head
Which artery causes locked in syndrome
Basilar artery
Acronym for features of migraine
POUNDing
Prophylaxis of Tension headache
Amitryptilline and acupuncture
Treatment of acute tension headache
NSAID and paracetamol
Treatment of acute migraine
Sumatriptan and ibuprofen
Prophylaxis of migraine
Propanolol
Symptoms of cluster headache
autonomic and one sided
How many counts as chronic tension headache
15 a month
Symptoms of migraine
Pounding, pulsatile, 4-72 hours, unilateral N and V, disabling
When do you operate on varicocele
More than 2cm, 20% volume or symptoms
Hydrocele description
Fluid collection which varies in size (operate if 2-21yrs old or infected)
What would you see on Ultrasound of a torsion testes
Whirlpool sign
Investigations for ED
Sexual health inventory for men
Glucose
Lipids
2 line treatment of ED
Intracavernous alprostadil suppository
3rd line treatment of ED
intraurethral alprostadil suppository
Investigation for renal colic
Non contrast KUB CT
Treatment of nephrolithiasis acutely
PR diclofenac and ondansetron
Treatment of urice acid renal stones
Allopurinol
Treatment of calcium renal stones
Indapamide
Treatment of oxalate renal stones
Calcium carbonate
Treatment of all renal stones
Pottasium citrate
BHcG is a tumour marker for which
Choriocarcinoma or seminoma
AFP is a tumour marker for which
Non seminoma
LDH is a tumour marker for which
Tumour burden
Investigation for testicular cancer
Ultrasound and tumour markers
Investigation for prostatic cancer
PR and PSA then TRUS (Transrectal US guided needle biopsy)
Treatment for prostate cancer when more than 10 years to live
Brachytherapy
Treatment for prostate cancer when high risk
Prostatectomy
Treatment for prostate cancer when metastatic
Androgen deprivation with lueprolin
third line treatment for BPH
Sildenafil
Non bothersome BPH treatment
Watchful waiting and behaviour management
What does BPH surgery choice depend on
TUIP, TURP or prostatectomy dependent on prostate volume
Nephrotic child treatment
MCD so give pred
Young adult nephrotic treatment
FSGN so ACE
Older person nephrotic treatment
IgA so ACE
Criteria for PCKD in under 30s
2 cysts
Criteria for PCKD in 30-60 year olds
2 cysts in each kidney
Criteria for PCKD in 60+ year olds
4 cysts in each kidney
Other considerations in PCKD
ECG and CT head as aneurysm and murmur risk
Pyelonephritis first investigations
MC and S of urine, blood culture and bloods (renal US)
Treatment of chlamydia
Azithromycin
Treatment for Gonorrhoea
Ceftriaxone and azithromycin
Causative organisms of prostatitis
E Coli
Treatment of prostatitis
Ciprofloxacin
Cystitis commonly caused by
E Coli
Cystitis treatment first line
3 days trimethoprim
Treatment of complicated cystitis
Ciprofloxacin
ECG changes in hypercalcaemia
Reduced QT interval
Osborn J waves
Arrythmias
Causes of hypocalcaemia
Parathyroidectomy
Vitamin D
Bisphosphonates
Hypocalcaemia ECG
Long QT
Arrythmias
Treatment of hypocalcaemia
IV calcium gluconate (then AdcalD3)
Name a vitamin D supplement
Colecalciferol
Diagnostic investigation of diabetes insipidus
Water deprivation test (wont concentrate urine)
Treatment of central diabetes insipidus
Desmopressin
Treatment of diabetes insipidus
Fluid intake
Treatment of SIADH
Fluid restriction
1st line investigation for conns
Serum aldosterone: renin ratio
Diagnostic investigation for conns
Fludrocortisone suppresion test
Treatment of Conns
Adrenalectomy or spironolactone
Acute treatment of addisons
IV hydrocortisone
Long term treatment of addisons
Hydrocortisone and fludrocortisone for life
Biochemistry in primary hyperparathyroidism
PTH high, calcium high, urine calcium low
Causes of primary hyperparathyroidism
Low calcium, parathyroidectomy, bisphophonates
Treatment of secondary hyperparathyroidism
Ergocalciferol
Signs of pseudohypoparathyroidism
Short 4th and 5th metacarpals, round face and short
Causes of hypoparathyroidism
Gland failure
Long term removal of pottasium from blood
Calcium resonium
Progress of ECG changes in hyperkalaemia
Peaked T waves, prolonged PR, flat P, wide QRS, sine wave, v fib, asystole
Upper limit of how much pottasium to give an hour
20mmol
ECG changes in hypokalaemia
ST depression, loss of T waves, long PR
Long acting insulin example
Insulin glargine
Education courses for diabetes
DAFNE- T1DM
DESMOND- T2DM
How long do you give 1L of fluid over in DKA
2,2,4,4,6
When do you escalate management of T2DM
When HbA1C still over 58
Treatment of increased sugar after meals in T2DM
Acarbose
MODY
Maturity onset diabetes of the young
Investigation for MODY
C peptide present
Treatment of MODY
Sulfonylurea
LADA
Latent autoimmune diabetes in adults
Treatment of LADA
Metformin, soon progresses to insulin
Diagnostic test for acromegaly
Oral glucose tolerance test
Treatment of acromegaly
Transphenoidal surgery
Ocreotide
Low ACTH in cushings syndrome suggests
Adrenal adenoma
Treatment of cushings disease
Pituitary MRI
Transphenoidal surgery
Renal cancer causes
Increased EPO and subsequent polycythaemia
Ovarian cancer causes
Hypoglycaemia
Medullary thyroid cancer causes
Increased calcitonin and subsequent hypocalcaemia
SCLC causes
SIADH
Lambert eaton
Cushings
Carcinoid tumours causes
serotonin syndrome
Squamous cancers cause
PTHrP relase and hypercalcaemia
Treatment of toxic multinodular goitre or toxic thyroid adenoma
Radioactive iodine
Investigation for thyrotoxicosis
Radioactive iodine uptake
Hypothyroid investigation
MRI incase pituitary adenoma
Tetracyclines example and side effect
Mirtazepine, weight gain
TCA side effects
Sedation, anticholingeric, cardiac arrythmias
SNRIs examples
Duloxetine, velafaxine
Examples of typical antipsychotics
Haloperidol
Chlorpromazine
Examples of atypical antipsychotics
Olanzapine, risperidone
Symptoms of anxiety (3 of which must be present most of the time)
Muscle tension, sleep disturbance, fatigue, restlessness, irritability, poor concentration
Methylphenidate side effect
Appetite suppression
Psychosis
Atoxemetine side effect
Liver dysfunction
Suicidality
Mild depression
2 core and 2 others
Moderate depression
2 core and 3 other
Severe depression
3 core and 4 others
Step wise medical management of depression
SSRI
TCA
SSRI and TCA
Define deliberate self harm
Self poisoning or injury, irrespective of apparent purpose of teh act
Tuberous sclerosis
Cognitive delary
Angiofibromas on cheeks
Ash leaf spots on spine
6 components of addiction
Tolerance Withdrawal Impaired control Continued use despite adverse consequences Compulsion to take Neglecting other activities
Section 2 of mental health act
Assess 28 days
Section 3 of mental health act
Treatment 6 months
Section 5.2 of mental health act
Doctors holding power, 72 hours
Conditions of mental capacity act
Assume they have capacity
Maximise their ability to make decisions
Unwise decisions doesnt mean you lack capacity
Anything done must be in best interests
Anything done must be least restrictive option
PD, isolated and restricted expression
Schizoid
PD, delusions and hates social interaction
Schizotypal