Occupational Lung Disease

Question 1

CXR small rounded opacities

Answer 1

silicosis

coal worker’s pneumoconiosis

Question 2

CXR small linear opacities

Answer 2

asbestosis

Question 3

an acute decrement of FEV1 over the first work shift of the week

Answer 3

cotton textile workers with byssinosis

Question 4

particles >10-15 m in diameter

Answer 4

do not penetrate beyond the nose and throat

Question 5

Particles deposited below the larynx

Answer 5

Particles

Question 6

contain crustal elements such as silica, aluminum, and iron. These particles mostly deposit relatively high in the tracheobronchial tree

Answer 6

Particles ~2.5-10 m (coarse-mode fraction)

Question 7

mesothelioma

Answer 7

Asbestos: mining, processing, construction, ship repair

Question 8

progressive massive fibrosis (PMF)

chronic obstructive pulmonary disease (COPD)

Answer 8

Silica: mining, stone cutting, sandblasting, quarrying

Question 9

Acute pneumonitis (rare), chronic granulomatous disease

Answer 9

Beryllium:

Question 10

Byssinosis (an asthma-like syndrome)
chronic bronchitis
COPD

Answer 10

Cotton dust

Question 11

diffuse interstitial fibrosing disease of the lung

at least 10 years before the disease becomes manifest

Answer 11

Asbestosis

Question 12

MOA fibrosis asbestosis

Answer 12

oxidative injury due to the generation of reactive oxygen species by the transition metals on the surface of the fibers

Question 13

subpleural curvilinear lines 5-10 mm in length that appear to be parallel to the pleural surface
indistinct heart border or a “ground-glass” appearance in the lung fields

Answer 13

asbestosis

Question 14

potential toxic agents can deposit and be carried to the lower airways

Question 15

ultrafine fraction and make up the largest number of particles;
remain in the airstream and deposit when in contact with alveolar walls

Question 16

the most common cancer associated with asbestos exposure

Answer 16

Lung cancer

Question 17

locally invasive tumors associated with asbestos exposure

in contrast to lung cancers, these tumors do not appear to be associated with smoking

Answer 17

Mesotheliomas

Question 18

characteristic HRCT pattern known as “crazy paving”

Answer 18

Silicosis

Question 19

CXR profuse miliary infiltration or consolidation

Answer 19

Silicosis

Question 20

Calcification of hilar nodes in 20%; “eggshell” pattern

Answer 20

Silicosis

Question 21

nodular fibrosis may be progressive in the absence of further exposure, with coalescence and formation of nonsegmental conglomerates of irregular masses >1 cm in diameter

Answer 21

complicated silicosis

small rounded opacities= simple

Question 22

small rounded opacities in the upper lobes may appear on the chest radiograph after 15–20 years of exposure

Answer 22

simple silicosis

Question 23

seropositiverheumatoid arthritis with characteristic pneumoconiotic nodules

Answer 23

Caplan’s syndrome