DVT Flashcards
two most common autosomal dominant genetic mutations
factor V Leiden
prothrombin gene mutation
two most common autosomal dominant genetic mutations
factor V Leiden
prothrombin gene mutation
defect in factor V Leiden
resistance to activated protein C (which inactivates clotting factors V and VIII)
most common gas exchange abnormalities DVT
hypoxemia (decreased arterial PO2)
increased alveolar-arterial O2 tension gradient
(represents the inefficiency of O2 transfer across the lungs)
usual cause of death from PE
Progressive right heart failure
usual cause of death from PE
Progressive right heart failure
patients who have DVT, the most common history
cramp in the lower calf
hypokinesis of the RV free wall with normal motion of the RV apex
McConnell’s sign
RV hypokinesis on echocardiography but normal systemic arterial pressure
moderate to large PE
massive PE=ystemic arterial hypotension and usually have anatomically widespread thromboembolism
MC history in PE
unexplained breathlessness
PE: focal oligemia
Westermark’s sign
PE: peripheral wedged-shaped density above the diaphragm
Hampton’s hump
PE: enlarged right descending pulmonary artery
Palla’s sign
D dimer increase
myocardial infarction
pneumonia, sepsis, cancer
postoperative state 2-3rd state
why d-dimer is a useful “rule out” test
More than 95% of patients with a normal (
