Occupational and Environmental Lung Disease

Question 1

Most common cancer associated with asbestos exposure. (Harrison’s 19th edition, pp 1689)

Answer 1

Lung cancer

Question 2

Monday chest tightness. (Harrison’s 19th edition, pp 1691)

Answer 2

Cotton dust (Byssinosis)

Question 3

Occupation lung disease that has a greater risk of acquiring pulmonary tuberculosis. (Harrison’s 19th edition, pp 1690)

Answer 3

Silicosis

Question 4

Characterized clinically as occasional (early-stage) and then regular (late-stage) chest tightness toward the end of the first day of the workweek. (Harrison’s 19th edition, pp 1691)

Answer 4

Cotton dust (Bysinossis)

Question 5

Chest radiographic hallmark of asbestosis. (Harrison’s 19th edition, pp 1689)

Answer 5

Irregular or linear opacities that usually are first noted in the lower lung fields

Question 6

This condition results from exposure to moldy hay containing spores of thermophilic actinomycetes that produce a hypersensitivity pneumonitis. (Harrison’s 19th edition, pp 1691)

Answer 6

Farmer’s lung

Question 7

Can produce giant cell interstitial pneumonitis. (Harrison’s 19th edition, pp 1691)

Answer 7

Tungsten carbide

Question 8

Characteristic HRCT pattern in silicosis. (Harrison’s 19th edition, pp 1690)

Answer 8

Crazy paving pattern

Question 9

It is the combination of pneumoconiotic nodules and seropositive arthritis. It was first described in coal miners but subsequently in patients with silicosis. (Harrison’s 19th edition, pp 1690)

Answer 9

Caplan syndrome

Question 10

Manifested by the appearance on the chest radiograph of nodules >/= 1cm in diameter generally confined to the upper half of the lungs. (Harrison’s 19th edition, pp 1690)

Answer 10

Complicated Coal Worker’s Pneumoconiosis

Question 11

Pulmonary function testing findings in asbestosis. (Harrison’s 19th edition, pp 1689)

Answer 11

Restrictive pattern

Decrease in both lung volumes and diffusing capacity

Question 12

Cause of the mild airflow obstruction in asbestosis. (Harrison’s 19th edition, pp 1689)

Answer 12

Peribronchiolar fibrosis

Question 13

Treatment for asbestosis. (Harrison’s 19th edition, pp 1689)

Answer 13

No specific therapy available

Supportive measures only

Question 14

A diffuse interstitial fibrosing disease of the lung that is directly related to the intensity and duration of exposure. (Harrison’s 19th edition, pp 1689)

Answer 14

Asbestosis

Question 15

Associated with asbestos exposure and does not appear to be associated with smoking. (Harrison’s 19th edition, pp 1689)

Answer 15

Mesotheliomas (pleural and peritoneal)

Question 16

Usually, exposure has taken place for at least ______ before the disease becomes manifest. (Harrison’s 19th edition, pp 1689)

Answer 16

10 years

Question 17

Persons at risk to asbestos exposure. (Harrison’s 19th edition, pp 1689)

Answer 17

Those who directly handle the material

Bystander exposure